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Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB

Overview of attention for article published in BMC Pharmacology and Toxicology, December 2014
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Title
Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB
Published in
BMC Pharmacology and Toxicology, December 2014
DOI 10.1186/2050-6511-15-73
Pubmed ID
Authors

Chad D Touchberry, Neerupma Silswal, Vladimir Tchikrizov, Christopher J Elmore, Shubra Srinivas, Adil S Akthar, Hannah K Swan, Lori A Wetmore, Michael J Wacker

Abstract

We have previously shown that the thromboxane (TXA2) receptor agonist, U46619, can directly induce ventricular arrhythmias that were associated with increases in intracellular calcium in cardiomyocytes. Since TXA2 is an inflammatory mediator and induces direct calcium changes in cardiomyocytes, we hypothesized that TXA2 released during ischemia or inflammation could also cause cardiac remodeling.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 20%
Student > Master 2 13%
Student > Doctoral Student 2 13%
Other 1 7%
Lecturer 1 7%
Other 1 7%
Unknown 5 33%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 3 20%
Agricultural and Biological Sciences 3 20%
Medicine and Dentistry 2 13%
Sports and Recreations 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Other 0 0%
Unknown 5 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2014.
All research outputs
#17,734,890
of 22,774,233 outputs
Outputs from BMC Pharmacology and Toxicology
#287
of 439 outputs
Outputs of similar age
#226,962
of 331,253 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#13
of 18 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 439 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,253 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.