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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Retinal vasculitis and ocular vitreous metastasis following complete response to PD-1 inhibition in a patient with metastatic cutaneous melanoma
|
|---|---|
| Published in |
Journal for Immunotherapy of Cancer, December 2014
|
| DOI | 10.1186/s40425-014-0041-1 |
| Pubmed ID | |
| Authors |
Joshua S Manusow, Leila Khoja, Nataly Pesin, Anthony M Joshua, Efrem D Mandelcorn |
| Abstract |
We report on a 36-year-old woman treated with the anti PD-1 antibody Pembrolizumab for metastatic cutaneous melanoma in the first line setting. She achieved a complete response and then relapsed with metastases to the vitreous cavity with an associated angiographically determined retinal vasculitis. Vitreous metastasis without choroidal involvement is unusual and may be due to individual cell extravasation, vitreous hemorrhage containing malignant cells, or direct spread through the optic nerve. This finding highlights the need for immune sanctuary sites to be monitored in the presence of PD-1 inhibition and we hypothesize that the use of PD-1 inhibitor potentiated the patient's angiographically determined retinal vasculitis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 2% |
| Unknown | 57 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 9 | 16% |
| Researcher | 7 | 12% |
| Student > Bachelor | 6 | 10% |
| Student > Ph. D. Student | 6 | 10% |
| Student > Postgraduate | 4 | 7% |
| Other | 9 | 16% |
| Unknown | 17 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 53% |
| Agricultural and Biological Sciences | 3 | 5% |
| Immunology and Microbiology | 2 | 3% |
| Mathematics | 1 | 2% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Other | 2 | 3% |
| Unknown | 18 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2023.
All research outputs
#5,288,711
of 25,394,764 outputs
Outputs from Journal for Immunotherapy of Cancer
#1,350
of 3,428 outputs
Outputs of similar age
#68,014
of 360,931 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#10
of 65 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,428 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,931 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.