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Novel H5 clade 2.3.4.6 viruses with both α-2,3 and α-2,6 receptor binding properties may pose a pandemic threat

Overview of attention for article published in Veterinary Research, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
5 X users

Citations

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28 Dimensions

Readers on

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25 Mendeley
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Title
Novel H5 clade 2.3.4.6 viruses with both α-2,3 and α-2,6 receptor binding properties may pose a pandemic threat
Published in
Veterinary Research, December 2014
DOI 10.1186/s13567-014-0127-2
Pubmed ID
Authors

Qunhui Li, Xuan Wang, Min Gu, Jie Zhu, Xiaoli Hao, Zhao Gao, Zhongtao Sun, Jiao Hu, Shunlin Hu, Xiaoquan Wang, Xiaowen Liu, Xiufan Liu

Abstract

The emerging H5 clade 2.3.4.6 viruses of different NA subtypes have been detected in different domestic poultry in China. We evaluated the receptor binding property and transmissibility of four novel H5 clade 2.3.4.6 subtype highly pathogenic avian influenza viruses. The results show that these viruses bound to both avian-type (α-2,3) and human-type (α-2,6) receptors. Furthermore, we found that one of these viruses, GS/EC/1112/11, not only replicated but also transmitted efficiently in guinea pigs. Therefore, such novel H5 subtype viruses have the potential of a pandemic threat.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
China 1 4%
Unknown 23 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 28%
Researcher 6 24%
Professor 3 12%
Student > Master 2 8%
Other 1 4%
Other 3 12%
Unknown 3 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 32%
Medicine and Dentistry 4 16%
Immunology and Microbiology 3 12%
Veterinary Science and Veterinary Medicine 2 8%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 3 12%
Unknown 4 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2015.
All research outputs
#3,212,340
of 25,374,917 outputs
Outputs from Veterinary Research
#124
of 1,337 outputs
Outputs of similar age
#40,821
of 347,668 outputs
Outputs of similar age from Veterinary Research
#1
of 16 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 347,668 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.