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Eyes-closed task-free electroencephalography in clinical trials for Alzheimer’s disease: an emerging method based upon brain dynamics

Overview of attention for article published in Alzheimer's Research & Therapy, December 2014
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  • Average Attention Score compared to outputs of the same age and source

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94 Mendeley
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Title
Eyes-closed task-free electroencephalography in clinical trials for Alzheimer’s disease: an emerging method based upon brain dynamics
Published in
Alzheimer's Research & Therapy, December 2014
DOI 10.1186/s13195-014-0086-x
Pubmed ID
Authors

Elisabeth CW van Straaten, Philip Scheltens, Alida A Gouw, Cornelis J Stam

Abstract

Electroencephalography (EEG) is a longstanding technique to measure electrical brain activity and thereby an indirect measure of synaptic activity. Synaptic dysfunction accompanies Alzheimer's disease (AD) and EEG can be regarded as a potentially useful biomarker in this disease. Lately, emerging analysis techniques of time series have become available for EEG, such as functional connectivity and network analysis, which have increased the possibilities for use in AD clinical trials. In this review, we report the EEG changes in the course of AD, including slowing of the EEG oscillations, decreased functional connectivity in the higher-frequency bands, and decline in optimal functional network organization. We discuss the use of EEG in clinical trials and provide directions for future research.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
United States 2 2%
Brazil 1 1%
Netherlands 1 1%
Denmark 1 1%
Italy 1 1%
Unknown 86 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 22%
Student > Ph. D. Student 18 19%
Student > Bachelor 9 10%
Student > Master 8 9%
Student > Doctoral Student 5 5%
Other 12 13%
Unknown 21 22%
Readers by discipline Count As %
Medicine and Dentistry 18 19%
Neuroscience 16 17%
Psychology 9 10%
Engineering 7 7%
Agricultural and Biological Sciences 6 6%
Other 15 16%
Unknown 23 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 May 2018.
All research outputs
#7,392,570
of 22,775,504 outputs
Outputs from Alzheimer's Research & Therapy
#1,036
of 1,211 outputs
Outputs of similar age
#104,617
of 353,125 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#10
of 15 outputs
Altmetric has tracked 22,775,504 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,211 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.2. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,125 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.