Title |
Interspecific and intraspecific gene variability in a 1-Mb region containing the highest density of NBS-LRR genes found in the melon genome
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1131 |
Pubmed ID | |
Authors |
Víctor M González, Núria Aventín, Emilio Centeno, Pere Puigdomènech |
Abstract |
Plant NBS-LRR pathogen-resistance genes tend to be found in clusters, which have been shown to be hot spots of genome variability, particularly in the form of presence/absence gene variation. In melon, half of the 81 predicted NBS-LRR genes group in nine clusters, and a 1 Mb region on linkage group V contains the highest density of R-genes and the highest concentration of PAV polymorphisms found in the melon genome. This region has been shown to contain the locus of Vat, an agronomically important gene that confers resistance to aphids. However, the presence of duplications makes the sequencing of R-gene clusters and their subsequent annotation difficult, usually resulting in multi-gapped sequences with higher than average errors. |
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