Title |
Categorizer: a tool to categorize genes into user-defined biological groups based on semantic similarity
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1091 |
Pubmed ID | |
Authors |
Dokyun Na, Hyungbin Son, Jörg Gsponer |
Abstract |
Communalities between large sets of genes obtained from high-throughput experiments are often identified by searching for enrichments of genes with the same Gene Ontology (GO) annotations. The GO analysis tools used for these enrichment analyses assume that GO terms are independent and the semantic distances between all parent-child terms are identical, which is not true in a biological sense. In addition these tools output lists of often redundant or too specific GO terms, which are difficult to interpret in the context of the biological question investigated by the user. Therefore, there is a demand for a robust and reliable method for gene categorization and enrichment analysis. |
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Geographical breakdown
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
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Spain | 1 | 1% |
Germany | 1 | 1% |
Unknown | 67 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 18 | 26% |
Student > Ph. D. Student | 14 | 20% |
Student > Master | 9 | 13% |
Student > Postgraduate | 5 | 7% |
Student > Doctoral Student | 4 | 6% |
Other | 12 | 17% |
Unknown | 7 | 10% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 27 | 39% |
Biochemistry, Genetics and Molecular Biology | 15 | 22% |
Computer Science | 3 | 4% |
Medicine and Dentistry | 3 | 4% |
Immunology and Microbiology | 2 | 3% |
Other | 5 | 7% |
Unknown | 14 | 20% |