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Calpain-5 gene expression in the mouse eye and brain

Overview of attention for article published in BMC Research Notes, November 2017
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Title
Calpain-5 gene expression in the mouse eye and brain
Published in
BMC Research Notes, November 2017
DOI 10.1186/s13104-017-2927-8
Pubmed ID
Authors

Kellie Schaefer, MaryAnn Mahajan, Anuradha Gore, Stephen H. Tsang, Alexander G. Bassuk, Vinit B. Mahajan

Abstract

Our objective was to characterize CAPN5 gene expression in the mouse central nervous system. Mouse brain and eye sections were probed with two high-affinity RNA oligonucleotide analogs designed to bind CAPN5 RNA and one scramble, control oligonucleotide. Images were captured in brightfield. CAPN5 RNA probes were validated on mouse breast cancer tumor tissue. In the eye, CAPN5 was expressed in the ganglion cell, inner nuclear and outer nuclear layers of the retina. Signal could not be detected in the ciliary body or the iris because of the high density of melanin. In the brain, CAPN5 was expressed in the granule cell layers of the hippocampus and cerebellum. There was scattered expression in pons. The visual cortex showed faint signal. Most signal in the brain was in a punctate pattern.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 17%
Student > Doctoral Student 2 11%
Researcher 2 11%
Student > Master 2 11%
Professor 1 6%
Other 2 11%
Unknown 6 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 28%
Medicine and Dentistry 3 17%
Neuroscience 1 6%
Agricultural and Biological Sciences 1 6%
Unknown 8 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2017.
All research outputs
#22,589,680
of 25,199,971 outputs
Outputs from BMC Research Notes
#3,794
of 4,497 outputs
Outputs of similar age
#386,870
of 450,590 outputs
Outputs of similar age from BMC Research Notes
#138
of 164 outputs
Altmetric has tracked 25,199,971 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,497 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 450,590 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 164 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.