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Short-term influence of cataract surgery on circadian biological rhythm and related health outcomes (CLOCK-IOL trial): study protocol for a randomized controlled trial

Overview of attention for article published in Trials, December 2014
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Title
Short-term influence of cataract surgery on circadian biological rhythm and related health outcomes (CLOCK-IOL trial): study protocol for a randomized controlled trial
Published in
Trials, December 2014
DOI 10.1186/1745-6215-15-514
Pubmed ID
Authors

Keigo Saeki, Kenji Obayashi, Tomo Nishi, Kimie Miyata, Shinji Maruoka, Tetsuo Ueda, Masahiro Okamoto, Taiji Hasegawa, Toyoaki Matsuura, Nobuhiro Tone, Nahoko Ogata, Norio Kurumatani

Abstract

Light information is the most important cue of circadian rhythm which synchronizes biological rhythm with external environment. Circadian misalignment of biological rhythm and external environment is associated with increased risk of depression, insomnia, obesity, diabetes, cardiovascular disease, and cancer.Increased light transmission by cataract surgery may improve circadian misalignment and related health outcomes. Although some observational studies have shown improvement of depression and insomnia after cataract surgery, randomized controlled trials are lacking. We will conduct a parallel-group, assessor-blinded, simple randomized controlled study comparing a cataract surgery group at three months after surgery with a control group to determine whether cataract surgery improves depressive symptoms, sleep quality, body mass regulation, and glucose and lipid metabolism.

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Mendeley readers

The data shown below were compiled from readership statistics for 250 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
India 1 <1%
Unknown 248 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 53 21%
Student > Master 30 12%
Researcher 27 11%
Student > Ph. D. Student 21 8%
Student > Doctoral Student 11 4%
Other 37 15%
Unknown 71 28%
Readers by discipline Count As %
Medicine and Dentistry 65 26%
Psychology 26 10%
Nursing and Health Professions 23 9%
Sports and Recreations 12 5%
Agricultural and Biological Sciences 9 4%
Other 32 13%
Unknown 83 33%