Title |
Short-term influence of cataract surgery on circadian biological rhythm and related health outcomes (CLOCK-IOL trial): study protocol for a randomized controlled trial
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Published in |
Trials, December 2014
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DOI | 10.1186/1745-6215-15-514 |
Pubmed ID | |
Authors |
Keigo Saeki, Kenji Obayashi, Tomo Nishi, Kimie Miyata, Shinji Maruoka, Tetsuo Ueda, Masahiro Okamoto, Taiji Hasegawa, Toyoaki Matsuura, Nobuhiro Tone, Nahoko Ogata, Norio Kurumatani |
Abstract |
Light information is the most important cue of circadian rhythm which synchronizes biological rhythm with external environment. Circadian misalignment of biological rhythm and external environment is associated with increased risk of depression, insomnia, obesity, diabetes, cardiovascular disease, and cancer.Increased light transmission by cataract surgery may improve circadian misalignment and related health outcomes. Although some observational studies have shown improvement of depression and insomnia after cataract surgery, randomized controlled trials are lacking. We will conduct a parallel-group, assessor-blinded, simple randomized controlled study comparing a cataract surgery group at three months after surgery with a control group to determine whether cataract surgery improves depressive symptoms, sleep quality, body mass regulation, and glucose and lipid metabolism. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
India | 1 | <1% |
Unknown | 248 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 53 | 21% |
Student > Master | 30 | 12% |
Researcher | 27 | 11% |
Student > Ph. D. Student | 21 | 8% |
Student > Doctoral Student | 11 | 4% |
Other | 37 | 15% |
Unknown | 71 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 65 | 26% |
Psychology | 26 | 10% |
Nursing and Health Professions | 23 | 9% |
Sports and Recreations | 12 | 5% |
Agricultural and Biological Sciences | 9 | 4% |
Other | 32 | 13% |
Unknown | 83 | 33% |