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Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages

Overview of attention for article published in Parasites & Vectors, March 2013
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Title
Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages
Published in
Parasites & Vectors, March 2013
DOI 10.1186/1756-3305-6-54
Pubmed ID
Authors

Izabela Coimbra Ibraim, Rafael Ramiro de Assis, Natália Lima Pessoa, Marco Antônio Campos, Maria Norma Melo, Salvatore Joseph Turco, Rodrigo Pedro Soares

Abstract

The dominant, cell surface lipophosphoglycan (LPG) of Leishmania is a multifunctional molecule involved in the interaction with vertebrate and invertebrate hosts. Although the role of LPG on infection has been extensively studied, it is not known if LPG interspecies variations contribute to the different immunopathologies of leishmaniases. To investigate the issue of interspecies polymorphisms, two Leishmania species from the New World that express structural variations of side chains of LPG repeat units were examined. In this context, the procyclic form of L. braziliensis LPG (strain M2903), is devoid of side chains, while the L. infantum LPG (strain BH46) has up to three glucoses residues in the repeat units.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 3%
Peru 1 <1%
Unknown 114 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 18%
Student > Bachelor 19 16%
Student > Doctoral Student 14 12%
Student > Ph. D. Student 14 12%
Researcher 13 11%
Other 12 10%
Unknown 25 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 27%
Biochemistry, Genetics and Molecular Biology 19 16%
Immunology and Microbiology 13 11%
Medicine and Dentistry 6 5%
Veterinary Science and Veterinary Medicine 5 4%
Other 12 10%
Unknown 31 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2015.
All research outputs
#20,248,338
of 22,776,824 outputs
Outputs from Parasites & Vectors
#4,840
of 5,457 outputs
Outputs of similar age
#171,127
of 194,853 outputs
Outputs of similar age from Parasites & Vectors
#42
of 44 outputs
Altmetric has tracked 22,776,824 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,457 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,853 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.