Title |
Nutrition, dietary interventions and prostate cancer: the latest evidence
|
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Published in |
BMC Medicine, January 2015
|
DOI | 10.1186/s12916-014-0234-y |
Pubmed ID | |
Authors |
Pao-Hwa Lin, William Aronson, Stephen J Freedland |
Abstract |
Prostate cancer (PCa) remains a leading cause of mortality in US men and the prevalence continues to rise world-wide especially in countries where men consume a 'Western-style' diet. Epidemiologic, preclinical and clinical studies suggest a potential role for dietary intake on the incidence and progression of PCa. 'This minireview provides an overview of recent published literature with regard to nutrients, dietary factors, dietary patterns and PCa incidence and progression. Low carbohydrates intake, soy protein, omega-3 (w-3) fat, green teas, tomatoes and tomato products and zyflamend showed promise in reducing PCa risk or progression. A higher saturated fat intake and a higher β-carotene status may increase risk. A 'U' shape relationship may exist between folate, vitamin C, vitamin D and calcium with PCa risk. Despite the inconsistent and inconclusive findings, the potential for a role of dietary intake for the prevention and treatment of PCa is promising. The combination of all the beneficial factors for PCa risk reduction in a healthy dietary pattern may be the best dietary advice. This pattern includes rich fruits and vegetables, reduced refined carbohydrates, total and saturated fats, and reduced cooked meats. Further carefully designed prospective trials are warranted. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 11 | 17% |
Spain | 10 | 15% |
United Kingdom | 7 | 11% |
Canada | 3 | 5% |
Finland | 2 | 3% |
Italy | 1 | 2% |
Germany | 1 | 2% |
Ireland | 1 | 2% |
Peru | 1 | 2% |
Other | 0 | 0% |
Unknown | 28 | 43% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 41 | 63% |
Practitioners (doctors, other healthcare professionals) | 17 | 26% |
Scientists | 7 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 2 | <1% |
United Kingdom | 2 | <1% |
Netherlands | 1 | <1% |
Mexico | 1 | <1% |
Denmark | 1 | <1% |
Nigeria | 1 | <1% |
Spain | 1 | <1% |
Unknown | 340 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 81 | 23% |
Student > Master | 54 | 15% |
Researcher | 29 | 8% |
Student > Ph. D. Student | 29 | 8% |
Student > Postgraduate | 16 | 5% |
Other | 52 | 15% |
Unknown | 88 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 100 | 29% |
Nursing and Health Professions | 41 | 12% |
Agricultural and Biological Sciences | 41 | 12% |
Biochemistry, Genetics and Molecular Biology | 29 | 8% |
Immunology and Microbiology | 6 | 2% |
Other | 34 | 10% |
Unknown | 98 | 28% |