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Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2

Overview of attention for article published in Molecular Cancer, October 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 1,326)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

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794 Facebook pages
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7 Google+ users

Citations

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70 Dimensions

Readers on

mendeley
55 Mendeley
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Title
Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2
Published in
Molecular Cancer, October 2010
DOI 10.1186/1476-4598-9-285
Pubmed ID
Authors

Mei Xu, Kimberly A Bower, Siying Wang, Jacqueline A Frank, Gang Chen, Min Ding, Shiow Wang, Xianglin Shi, Zunji Ke, Jia Luo

Abstract

Ethanol is a tumor promoter. Both epidemiological and experimental studies suggest that ethanol may enhance the metastasis of breast cancer cells. We have previously demonstrated that ethanol increased the migration/invasion of breast cancer cells expressing high levels of ErbB2. Amplification of ErbB2 is found in 20-30% of breast cancer patients and is associated with poor prognosis. We sought to identify agents that can prevent or ameliorate ethanol-induced invasion of breast cancer cells. Cyanidin-3-glucoside (C3G), an anthocyanin present in many vegetables and fruits, is a potent natural antioxidant. Ethanol exposure causes the accumulation of intracellular reactive oxygen species (ROS). This study evaluated the effect of C3G on ethanol-induced breast cancer cell migration/invasion.

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
China 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 16%
Student > Ph. D. Student 7 13%
Student > Master 6 11%
Researcher 4 7%
Student > Postgraduate 4 7%
Other 9 16%
Unknown 16 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 25%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Medicine and Dentistry 5 9%
Biochemistry, Genetics and Molecular Biology 4 7%
Chemistry 3 5%
Other 5 9%
Unknown 19 35%

Attention Score in Context

This research output has an Altmetric Attention Score of 87. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2020.
All research outputs
#276,075
of 16,791,453 outputs
Outputs from Molecular Cancer
#6
of 1,326 outputs
Outputs of similar age
#5,025
of 308,772 outputs
Outputs of similar age from Molecular Cancer
#2
of 37 outputs
Altmetric has tracked 16,791,453 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,326 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 308,772 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.