↓ Skip to main content

Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study

Overview of attention for article published in Respiratory Research, January 2015
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

twitter
5 tweeters
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
48 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study
Published in
Respiratory Research, January 2015
DOI 10.1186/s12931-015-0166-x
Pubmed ID
Authors

Daniela Kuguimoto Andaku, Vânia D’Almeida, Gláucia Carneiro, Sônia Hix, Sergio Tufik, Sônia Maria Togeiro

Abstract

BackgroundThe simultaneous occurrence of metabolic syndrome and excessive daytime sleepiness are very common in obstructive sleep apnea (OSA) patients. Both conditions, if present in OSA, have been reported to be associated with inflammation and disruption of oxidative stress balance that impair the cardiovascular system. To verify the impact of daytime sleepiness on inflammatory and oxidative stress markers, we evaluated OSA patients without significant metabolic disturbance.MethodsThirty-five male subjects without diagnostic criteria for metabolic syndrome (Adult Treatment Panel III) were distributed into a control group (n¿=¿10) (43¿±¿10.56 years, apnea-hypopnea index - AHI 2.71¿±¿1.48/hour), a non-sleepy OSA group (n¿=¿11) (42.36¿±¿9.48 years, AHI 29.48¿±¿22.83/hour) and a sleepy OSA group (n¿=¿14) (45.43¿±¿10.06 years, AHI 38.20¿±¿25.54/hour). Excessive daytime sleepiness was considered when Epworth sleepiness scale score was¿¿¿10. Levels of high-sensitivity C-reactive protein, homocysteine and cysteine, and paraoxonase-1 activity and arylesterase activity of paraoxonase-1 were evaluated.ResultsPatients with OSA and excessive daytime sleepiness presented increased high-sensitivity C-reactive protein levels even after controlling for confounders. No significant differences were found among the groups in paraoxonase-1 activity nor arylesterase activity of paraoxonase-1. AHI was independently associated and excessive daytime sleepiness tended to have an association with high-sensitivity C-reactive protein.ConclusionsIn the absence of metabolic syndrome, increased inflammatory response was associated with AHI and daytime sleepiness, while OSA was not associated with abnormalities in oxidative stress markers.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 19%
Student > Ph. D. Student 7 15%
Researcher 5 10%
Student > Doctoral Student 4 8%
Student > Master 4 8%
Other 6 13%
Unknown 13 27%
Readers by discipline Count As %
Medicine and Dentistry 17 35%
Nursing and Health Professions 3 6%
Neuroscience 3 6%
Agricultural and Biological Sciences 2 4%
Arts and Humanities 2 4%
Other 4 8%
Unknown 17 35%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2016.
All research outputs
#3,327,430
of 12,537,999 outputs
Outputs from Respiratory Research
#406
of 1,467 outputs
Outputs of similar age
#81,415
of 323,499 outputs
Outputs of similar age from Respiratory Research
#20
of 89 outputs
Altmetric has tracked 12,537,999 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,467 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,499 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.