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Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum

Overview of attention for article published in Malaria Journal, April 2014
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1 X user

Citations

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99 Mendeley
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Title
Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum
Published in
Malaria Journal, April 2014
DOI 10.1186/1475-2875-13-142
Pubmed ID
Authors

Talita PC Chierrito, Anna CC Aguiar, Isabel M de Andrade, Isabela P Ceravolo, Regina AC Gonçalves, Arildo JB de Oliveira, Antoniana U Krettli

Abstract

Several species of Aspidosperma (Apocynaceae) are used as treatments for human diseases in the tropics. Aspidosperma olivaceum, which is used to treat fevers in some regions of Brazil, contains the monoterpenoid indole alkaloids (MIAs) aspidoscarpine, uleine, apparicine, and N-methyl-tetrahydrolivacine. Using bio-guided fractionation and cytotoxicity testing in a human hepatoma cell line, several plant fractions and compounds purified from the bark and leaves of the plant were characterized for specific therapeutic activity (and selectivity index, SI) in vitro against the blood forms of Plasmodium falciparum.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
South Africa 1 1%
Unknown 97 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 19%
Researcher 11 11%
Student > Master 10 10%
Student > Doctoral Student 8 8%
Student > Bachelor 8 8%
Other 18 18%
Unknown 25 25%
Readers by discipline Count As %
Chemistry 22 22%
Agricultural and Biological Sciences 14 14%
Pharmacology, Toxicology and Pharmaceutical Science 13 13%
Medicine and Dentistry 9 9%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 13 13%
Unknown 24 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2015.
All research outputs
#15,315,142
of 22,778,347 outputs
Outputs from Malaria Journal
#4,467
of 5,557 outputs
Outputs of similar age
#133,902
of 227,018 outputs
Outputs of similar age from Malaria Journal
#62
of 101 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,557 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,018 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.