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CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

Overview of attention for article published in Journal for Immunotherapy of Cancer, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

twitter
3 tweeters
patent
5 patents

Citations

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41 Dimensions

Readers on

mendeley
73 Mendeley
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Title
CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy
Published in
Journal for Immunotherapy of Cancer, December 2014
DOI 10.1186/s40425-014-0046-9
Pubmed ID
Authors

Christopher L Moertel, Junzhe Xia, Rebecca LaRue, Nate N Waldron, Brian M Andersen, Robert M Prins, Hideho Okada, Andrew M Donson, Nicholas K Foreman, Matthew A Hunt, Christopher A Pennell, Michael R Olin

Abstract

Immunological quiescence in the central nervous system (CNS) is a potential barrier to immune mediated anti-tumor response. One suppressive mechanism results from the interaction of parenchyma-derived CD200 and its receptor on myeloid cells. We suggest that CD200/CD200R interactions on myeloid cells expand the myeloid-derived suppressor cell (MDSC) population and that blocking tumor-derived CD200 will enhance the efficacy of immunotherapy.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 22%
Student > Ph. D. Student 12 16%
Student > Bachelor 10 14%
Student > Master 6 8%
Student > Doctoral Student 4 5%
Other 11 15%
Unknown 14 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 21%
Biochemistry, Genetics and Molecular Biology 13 18%
Medicine and Dentistry 13 18%
Immunology and Microbiology 8 11%
Neuroscience 4 5%
Other 2 3%
Unknown 18 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2021.
All research outputs
#2,368,772
of 19,957,201 outputs
Outputs from Journal for Immunotherapy of Cancer
#541
of 2,311 outputs
Outputs of similar age
#37,728
of 312,313 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#3
of 21 outputs
Altmetric has tracked 19,957,201 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,311 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,313 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.