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CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

Overview of attention for article published in Journal for Immunotherapy of Cancer, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

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2 X users
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7 patents

Citations

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57 Dimensions

Readers on

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89 Mendeley
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Title
CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy
Published in
Journal for Immunotherapy of Cancer, December 2014
DOI 10.1186/s40425-014-0046-9
Pubmed ID
Authors

Christopher L Moertel, Junzhe Xia, Rebecca LaRue, Nate N Waldron, Brian M Andersen, Robert M Prins, Hideho Okada, Andrew M Donson, Nicholas K Foreman, Matthew A Hunt, Christopher A Pennell, Michael R Olin

Abstract

Immunological quiescence in the central nervous system (CNS) is a potential barrier to immune mediated anti-tumor response. One suppressive mechanism results from the interaction of parenchyma-derived CD200 and its receptor on myeloid cells. We suggest that CD200/CD200R interactions on myeloid cells expand the myeloid-derived suppressor cell (MDSC) population and that blocking tumor-derived CD200 will enhance the efficacy of immunotherapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 89 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 20%
Student > Ph. D. Student 14 16%
Student > Bachelor 11 12%
Student > Master 6 7%
Student > Doctoral Student 4 4%
Other 12 13%
Unknown 24 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 18%
Agricultural and Biological Sciences 15 17%
Medicine and Dentistry 13 15%
Immunology and Microbiology 9 10%
Neuroscience 4 4%
Other 4 4%
Unknown 28 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2023.
All research outputs
#3,274,275
of 25,371,288 outputs
Outputs from Journal for Immunotherapy of Cancer
#894
of 3,421 outputs
Outputs of similar age
#43,113
of 360,766 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#7
of 65 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,766 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.