Title |
Maternal immunity enhances Mycoplasma hyopneumoniaevaccination induced cell-mediated immune responses in piglets
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Published in |
BMC Veterinary Research, June 2014
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DOI | 10.1186/1746-6148-10-124 |
Pubmed ID | |
Authors |
Meggan Bandrick, Kara Theis, Thomas W Molitor |
Abstract |
Passively acquired maternal derived immunity (MDI) is a double-edged sword. Maternal derived antibody-mediated immunity (AMI) and cell-mediated immunity (CMI) are critical immediate defenses for the neonate; however, MDI may interfere with the induction of active immunity in the neonate, i.e. passive interference. The effect of antigen-specific MDI on vaccine-induced AMI and CMI responses to Mycoplasma hyopneumoniae (M. hyopneumoniae) was assessed in neonatal piglets. To determine whether CMI and AMI responses could be induced in piglets with MDI, piglets with high and low levels of maternal M. hyopneumoniae-specific immunity were vaccinated against M. hyopneumoniae at 7 d of age. Piglet M. hyopneumoniae-specific antibody, lymphoproliferation, and delayed type hypersensitivity (DTH) responses were measured 7 d and 14 d post vaccination. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 2% |
Spain | 1 | 2% |
Unknown | 56 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 13 | 22% |
Student > Ph. D. Student | 11 | 19% |
Student > Master | 10 | 17% |
Student > Bachelor | 4 | 7% |
Student > Doctoral Student | 3 | 5% |
Other | 12 | 21% |
Unknown | 5 | 9% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 18 | 31% |
Veterinary Science and Veterinary Medicine | 17 | 29% |
Medicine and Dentistry | 6 | 10% |
Immunology and Microbiology | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 2 | 3% |
Unknown | 10 | 17% |