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Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review

Overview of attention for article published in BMC Infectious Diseases, December 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
1 tweeter
wikipedia
1 Wikipedia page

Citations

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16 Dimensions

Readers on

mendeley
45 Mendeley
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Title
Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review
Published in
BMC Infectious Diseases, December 2017
DOI 10.1186/s12879-017-2896-5
Pubmed ID
Authors

Shigeo Iijima

Abstract

Isolated congenital asplenia (ICA) is a rare and life-threatening condition that predisposes patients to severe bacterial infections. Most of the reported cases are familial and the mode of inheritance is usually autosomal dominant. Here, we report a case of sporadic isolated asplenia and review the literature while focusing on sporadic cases. We report the case of an 11-month-old female infant who developed fulminant pneumococcal meningitis. The pneumococcal vaccine-unimmunized patient was hospitalized with fever, irritability, and purpura, and was diagnosed as having meningitis, septic shock, and disseminated intravascular coagulation. Streptococcus pneumoniae was isolated from both cerebrospinal fluid and blood. She was successfully treated with prompt antibiotic therapy. During hospitalization, abdominal ultrasonography and computed tomography findings, scintigraphy results, and Howell-Jolly body-containing red blood cells indicated the presence of asplenia without any visceroarterial anomalies. Moreover, the findings of peripheral blood smears and spleen ultrasonographic examinations of her parents were normal. Majority of sporadic ICA cases were detected only after the onset of overwhelming infection and had a high mortality. In cases of severe invasive pneumococcal disease, a systematic search for Howell-Jolly bodies on blood smears and the presence of asplenia on abdominal imaging are essential for detecting ICA even in the absence of any family history. After the diagnosis of ICA, patient and parent education, vaccinations, antibiotic prophylaxis, and prompt empiric treatment of febrile episode should be provided.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 8 18%
Student > Master 5 11%
Student > Postgraduate 4 9%
Student > Ph. D. Student 4 9%
Student > Bachelor 3 7%
Other 8 18%
Unknown 13 29%
Readers by discipline Count As %
Medicine and Dentistry 17 38%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Agricultural and Biological Sciences 2 4%
Immunology and Microbiology 1 2%
Nursing and Health Professions 1 2%
Other 2 4%
Unknown 20 44%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2019.
All research outputs
#6,324,236
of 20,886,305 outputs
Outputs from BMC Infectious Diseases
#2,016
of 7,171 outputs
Outputs of similar age
#147,649
of 438,737 outputs
Outputs of similar age from BMC Infectious Diseases
#213
of 657 outputs
Altmetric has tracked 20,886,305 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 7,171 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 438,737 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 657 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.