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Mendeley readers
Attention Score in Context
| Title |
Intracellular gold nanoparticles enhance non-invasive radiofrequency thermal destruction of human gastrointestinal cancer cells
|
|---|---|
| Published in |
Journal of Nanobiotechnology, January 2008
|
| DOI | 10.1186/1477-3155-6-2 |
| Pubmed ID | |
| Authors |
Christopher J Gannon, Chitta Ranjan Patra, Resham Bhattacharya, Priyabrata Mukherjee, Steven A Curley |
| Abstract |
Novel approaches to treat human cancer that are effective with minimal toxicity profiles are needed. We evaluated gold nanoparticles (GNPs) in human hepatocellular and pancreatic cancer cells to determine: 1) absence of intrinsic cytotoxicity of the GNPs and 2) external radiofrequency (RF) field-induced heating of intracellular GNPs to produce thermal destruction of malignant cells. GNPs (5 nm diameter) were added to 2 human cancer cell lines (Panc-1, Hep3B). 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and propidium iodide-fluorescence associated cell sorting (PI-FACS) assessed cell proliferation and GNP-related cytotoxicity. Other GNP-treated cells were exposed to a 13.56 MHz RF field for 1, 2, or 5 minutes, and then incubated for 24 hours. PI-FACS measured RF-induced cytotoxicity. |
Mendeley readers
The data shown below were compiled from readership statistics for 231 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 1% |
| United States | 2 | <1% |
| India | 1 | <1% |
| Germany | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Ukraine | 1 | <1% |
| Belgium | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 220 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 65 | 28% |
| Researcher | 42 | 18% |
| Student > Master | 19 | 8% |
| Student > Bachelor | 18 | 8% |
| Professor > Associate Professor | 18 | 8% |
| Other | 37 | 16% |
| Unknown | 32 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 24% |
| Chemistry | 32 | 14% |
| Engineering | 24 | 10% |
| Medicine and Dentistry | 19 | 8% |
| Biochemistry, Genetics and Molecular Biology | 16 | 7% |
| Other | 46 | 20% |
| Unknown | 39 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2015.
All research outputs
#20,249,662
of 22,778,347 outputs
Outputs from Journal of Nanobiotechnology
#1,209
of 1,405 outputs
Outputs of similar age
#151,584
of 156,519 outputs
Outputs of similar age from Journal of Nanobiotechnology
#2
of 2 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,405 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,519 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.