Title |
The human microbiome in evolution
|
---|---|
Published in |
BMC Biology, December 2017
|
DOI | 10.1186/s12915-017-0454-7 |
Pubmed ID | |
Authors |
Emily R. Davenport, Jon G. Sanders, Se Jin Song, Katherine R. Amato, Andrew G. Clark, Rob Knight |
Abstract |
The trillions of microbes living in the gut-the gut microbiota-play an important role in human biology and disease. While much has been done to explore its diversity, a full understanding of our microbiomes demands an evolutionary perspective. In this review, we compare microbiomes from human populations, placing them in the context of microbes from humanity's near and distant animal relatives. We discuss potential mechanisms to generate host-specific microbiome configurations and the consequences of disrupting those configurations. Finally, we propose that this broader phylogenetic perspective is useful for understanding the mechanisms underlying human-microbiome interactions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 56 | 21% |
United Kingdom | 18 | 7% |
Spain | 11 | 4% |
France | 10 | 4% |
Australia | 8 | 3% |
Canada | 8 | 3% |
Sweden | 7 | 3% |
Germany | 7 | 3% |
Denmark | 4 | 1% |
Other | 45 | 17% |
Unknown | 96 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 130 | 48% |
Scientists | 123 | 46% |
Practitioners (doctors, other healthcare professionals) | 9 | 3% |
Science communicators (journalists, bloggers, editors) | 8 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 820 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 118 | 14% |
Student > Ph. D. Student | 114 | 14% |
Student > Master | 106 | 13% |
Researcher | 95 | 12% |
Student > Doctoral Student | 49 | 6% |
Other | 113 | 14% |
Unknown | 225 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 166 | 20% |
Biochemistry, Genetics and Molecular Biology | 150 | 18% |
Immunology and Microbiology | 68 | 8% |
Medicine and Dentistry | 66 | 8% |
Environmental Science | 20 | 2% |
Other | 103 | 13% |
Unknown | 247 | 30% |