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Human neural stem cell transplantation in ALS: initial results from a phase I trial

Overview of attention for article published in Journal of Translational Medicine, January 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
4 news outlets
twitter
8 X users
facebook
3 Facebook pages

Readers on

mendeley
214 Mendeley
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Title
Human neural stem cell transplantation in ALS: initial results from a phase I trial
Published in
Journal of Translational Medicine, January 2015
DOI 10.1186/s12967-014-0371-2
Pubmed ID
Authors

Letizia Mazzini, Maurizio Gelati, Daniela Profico, Giada Sgaravizzi, Massimo Projetti Pensi, Gianmarco Muzi, Claudia Ricciolini, Laura Rota Nodari, Sandro Carletti, Cesare Giorgi, Cristina Spera, Frondizi Domenico, Enrica Bersano, Francesco Petruzzelli, Carlo Cisari, Annamaria Maglione, Maria Sarnelli, Alessandro Stecco, Giorgia Querin, Stefano Masiero, Roberto Cantello, Daniela Ferrari, Cristina Zalfa, Elena Binda, Alberto Visioli, Domenico Trombetta, Antonio Novelli, Barbara Torres, Laura Bernardini, Alessandro Carriero, Paolo Prandi, Serena Servo, Annalisa Cerino, Valentina Cima, Alessandra Gaiani, Nicola Nasuelli, Maurilio Massara, Jonathan Glass, Gianni Sorarù, Nicholas M Boulis, Angelo L Vescovi

Abstract

We report the initial results from a phase I clinical trial for ALS. We transplanted GMP-grade, fetal human neural stem cells from natural in utero death (hNSCs) into the anterior horns of the spinal cord to test for the safety of both cells and neurosurgical procedures in these patients. The trial was approved by the Istituto Superiore di Sanità and the competent Ethics Committees and was monitored by an external Safety Board.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 214 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 <1%
Italy 1 <1%
Canada 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 209 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 38 18%
Student > Master 30 14%
Student > Bachelor 29 14%
Researcher 28 13%
Other 9 4%
Other 28 13%
Unknown 52 24%
Readers by discipline Count As %
Medicine and Dentistry 31 14%
Biochemistry, Genetics and Molecular Biology 30 14%
Neuroscience 29 14%
Agricultural and Biological Sciences 27 13%
Nursing and Health Professions 8 4%
Other 29 14%
Unknown 60 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2018.
All research outputs
#912,169
of 22,780,165 outputs
Outputs from Journal of Translational Medicine
#164
of 3,987 outputs
Outputs of similar age
#13,234
of 352,944 outputs
Outputs of similar age from Journal of Translational Medicine
#5
of 140 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,987 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,944 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.