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Hepatitis B virus infection in hilly/mountainous regions of southeastern China: a locality-dependent epidemiology

Overview of attention for article published in BMC Infectious Diseases, December 2017
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Title
Hepatitis B virus infection in hilly/mountainous regions of southeastern China: a locality-dependent epidemiology
Published in
BMC Infectious Diseases, December 2017
DOI 10.1186/s12879-017-2922-7
Pubmed ID
Authors

Ping Chen, Qinfen Xie, Ting Chen, Jiawei Wu, Jie Wu, Bing Ruan, Zhiqin Zhang, Hainv Gao, Lanjuan Li

Abstract

The overall prevalence of hepatitis B virus (HBV) infection in China is declining. The purpose of this study was to use a community-based epidemiological study to update the infection status of hepatitis B virus (HBV) in mountainous regions of China, and to evaluate the impact of the Expanded Program of Immunization (EPI) on HBV transmission. In total, 10,383 participants were selected by multi-stage stratified random cluster sampling in two mountainous regions, Xianju and Anji, in Zhejiang province, China. The positive rates of hepatitis B virus surface antigen (HBsAg), anti-HBV core antigen (anti-HBc), and anti-HBV surface antigen (anti-HBs) were 9.5%, 33.9%, and 51.0%, respectively. Positive HBV markers were more frequently detected in males than in females (P < 0.01). The alanine aminotransferase (ALT) levels were elevated (>38 IU/L) in 15.3% of the HBsAg-positive and 6.3% of the HBsAg-negative subjects. The α-fetoprotein (AFP) level was elevated in 0.8% of the HBsAg-positive participants who were older than 30 years old. The epidemiology of HBV infection is location dependent. The prevalence of HBV infection in the mountainous regions is higher than the national levels. Moreover, HBV infection in women of childbearing age is up to 10%, which represents a main factor for continuous HBV transmission.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 11%
Researcher 2 11%
Other 1 6%
Student > Ph. D. Student 1 6%
Professor 1 6%
Other 2 11%
Unknown 9 50%
Readers by discipline Count As %
Nursing and Health Professions 2 11%
Medicine and Dentistry 2 11%
Biochemistry, Genetics and Molecular Biology 1 6%
Arts and Humanities 1 6%
Engineering 1 6%
Other 0 0%
Unknown 11 61%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2018.
All research outputs
#20,458,307
of 23,015,156 outputs
Outputs from BMC Infectious Diseases
#6,520
of 7,723 outputs
Outputs of similar age
#377,542
of 441,864 outputs
Outputs of similar age from BMC Infectious Diseases
#135
of 165 outputs
Altmetric has tracked 23,015,156 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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We're also able to compare this research output to 165 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.