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Gene function classification using Bayesian models with hierarchy-based priors

Overview of attention for article published in BMC Bioinformatics, October 2006
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2 Wikipedia pages

Citations

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20 Dimensions

Readers on

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32 Mendeley
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2 CiteULike
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Title
Gene function classification using Bayesian models with hierarchy-based priors
Published in
BMC Bioinformatics, October 2006
DOI 10.1186/1471-2105-7-448
Pubmed ID
Authors

Babak Shahbaba, Radford M Neal

Abstract

We investigate whether annotation of gene function can be improved using a classification scheme that is aware that functional classes are organized in a hierarchy. The classifiers look at phylogenic descriptors, sequence based attributes, and predicted secondary structure. We discuss three Bayesian models and compare their performance in terms of predictive accuracy. These models are the ordinary multinomial logit (MNL) model, a hierarchical model based on a set of nested MNL models, and an MNL model with a prior that introduces correlations between the parameters for classes that are nearby in the hierarchy. We also provide a new scheme for combining different sources of information. We use these models to predict the functional class of Open Reading Frames (ORFs) from the E. coli genome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 13%
France 1 3%
Canada 1 3%
Brazil 1 3%
Unknown 25 78%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 22%
Professor > Associate Professor 6 19%
Student > Ph. D. Student 5 16%
Researcher 3 9%
Student > Doctoral Student 3 9%
Other 5 16%
Unknown 3 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 28%
Computer Science 8 25%
Engineering 4 13%
Mathematics 4 13%
Medicine and Dentistry 2 6%
Other 2 6%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2018.
All research outputs
#7,451,284
of 22,780,165 outputs
Outputs from BMC Bioinformatics
#3,020
of 7,277 outputs
Outputs of similar age
#23,188
of 66,307 outputs
Outputs of similar age from BMC Bioinformatics
#9
of 44 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,277 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 50% of its peers.
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