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Overview of attention for article published in Nutrition & Metabolism, January 2004
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)

Mentioned by

1 tweeter
1 patent
1 Facebook page


286 Dimensions

Readers on

156 Mendeley
1 CiteULike
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Published in
Nutrition & Metabolism, January 2004
DOI 10.1186/1743-7075-1-10
Pubmed ID

Melvin R Hayden, Suresh C Tyagi


BACKGROUND: The topical role of uric acid and its relation to cardiovascular disease, renal disease, and hypertension is rapidly evolving. Its important role both historically and currently in the clinical clustering phenomenon of the metabolic syndrome (MS), type 2 diabetes mellitus (T2DM), atheroscleropathy, and non-diabetic atherosclerosis is of great importance. RESULTS: Uric acid is a marker of risk and it remains controversial as to its importance as a risk factor (causative role). In this review we will attempt to justify its important role as one of the many risk factors in the development of accelerated atherosclerosis and discuss its importance of being one of the multiple injurious stimuli to the endothelium, the arterial vessel wall, and capillaries. The role of uric acid, oxidative - redox stress, reactive oxygen species, and decreased endothelial nitric oxide and endothelial dysfunction cannot be over emphasized.In the atherosclerotic prooxidative environmental milieu the original antioxidant properties of uric acid paradoxically becomes prooxidant, thus contributing to the oxidation of lipoproteins within atherosclerotic plaques, regardless of their origins in the MS, T2DM, accelerated atherosclerosis (atheroscleropathy), or non-diabetic vulnerable atherosclerotic plaques. In this milieu there exists an antioxidant - prooxidant urate redox shuttle. CONCLUSION: Elevations of uric acid > 4 mg/dl should be considered a "red flag" in those patients at risk for cardiovascular disease and should alert the clinician to strive to utilize a global risk reduction program in a team effort to reduce the complications of the atherogenic process resulting in the morbid - mortal outcomes of cardiovascular disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 2 1%
United States 1 <1%
United Kingdom 1 <1%
Australia 1 <1%
Unknown 151 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 25 16%
Researcher 21 13%
Student > Ph. D. Student 20 13%
Student > Bachelor 19 12%
Student > Postgraduate 16 10%
Other 38 24%
Unknown 17 11%
Readers by discipline Count As %
Medicine and Dentistry 63 40%
Agricultural and Biological Sciences 20 13%
Biochemistry, Genetics and Molecular Biology 16 10%
Nursing and Health Professions 5 3%
Neuroscience 4 3%
Other 24 15%
Unknown 24 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2019.
All research outputs
of 19,911,970 outputs
Outputs from Nutrition & Metabolism
of 881 outputs
Outputs of similar age
of 313,278 outputs
Outputs of similar age from Nutrition & Metabolism
of 3 outputs
Altmetric has tracked 19,911,970 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 881 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.1. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,278 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.