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High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction

Overview of attention for article published in BioMedical Engineering OnLine, November 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

patent
3 patents
wikipedia
8 Wikipedia pages

Citations

dimensions_citation
271 Dimensions

Readers on

mendeley
214 Mendeley
citeulike
1 CiteULike
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Title
High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction
Published in
BioMedical Engineering OnLine, November 2011
DOI 10.1186/1475-925x-10-102
Pubmed ID
Authors

Christopher B Arena, Michael B Sano, John H Rossmeisl, John L Caldwell, Paulo A Garcia, Marissa Nichole Rylander, Rafael V Davalos

Abstract

Therapeutic irreversible electroporation (IRE) is an emerging technology for the non-thermal ablation of tumors. The technique involves delivering a series of unipolar electric pulses to permanently destabilize the plasma membrane of cancer cells through an increase in transmembrane potential, which leads to the development of a tissue lesion. Clinically, IRE requires the administration of paralytic agents to prevent muscle contractions during treatment that are associated with the delivery of electric pulses. This study shows that by applying high-frequency, bipolar bursts, muscle contractions can be eliminated during IRE without compromising the non-thermal mechanism of cell death.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 214 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Unknown 212 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 21%
Researcher 36 17%
Student > Bachelor 19 9%
Student > Master 17 8%
Student > Doctoral Student 13 6%
Other 31 14%
Unknown 53 25%
Readers by discipline Count As %
Engineering 56 26%
Medicine and Dentistry 37 17%
Biochemistry, Genetics and Molecular Biology 20 9%
Agricultural and Biological Sciences 18 8%
Physics and Astronomy 4 2%
Other 18 8%
Unknown 61 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2024.
All research outputs
#5,240,914
of 24,682,395 outputs
Outputs from BioMedical Engineering OnLine
#135
of 851 outputs
Outputs of similar age
#42,420
of 249,034 outputs
Outputs of similar age from BioMedical Engineering OnLine
#9
of 25 outputs
Altmetric has tracked 24,682,395 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 851 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,034 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.