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Mendeley readers
Attention Score in Context
| Title |
RLIP76, a non-ABC transporter, and drug resistance in epilepsy
|
|---|---|
| Published in |
BMC Neuroscience, September 2005
|
| DOI | 10.1186/1471-2202-6-61 |
| Pubmed ID | |
| Authors |
Sanjay Awasthi, Kerri L Hallene, Vince Fazio, Sharad S Singhal, Luca Cucullo, Yogesh C Awasthi, Gabriele Dini, Damir Janigro |
| Abstract |
Permeability of the blood-brain barrier is one of the factors determining the bioavailability of therapeutic drugs and resistance to chemically different antiepileptic drugs is a consequence of decreased intracerebral accumulation. The ABC transporters, particularly P-glycoprotein, are known to play a role in antiepileptic drug extrusion, but are not by themselves sufficient to fully explain the phenomenon of drug-resistant epilepsy. Proteomic analyses of membrane protein differentially expressed in epileptic foci brain tissue revealed the frequently increased expression of RLIP76/RALBP1, a recently described non-ABC multi-specific transporter. Because of a significant overlap in substrates between P-glycoprotein and RLIP76, present studies were carried out to determine the potential role of RLIP76 in AED transport in the brain. |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ethiopia | 1 | 1% |
| France | 1 | 1% |
| Brazil | 1 | 1% |
| United Kingdom | 1 | 1% |
| New Zealand | 1 | 1% |
| Spain | 1 | 1% |
| Japan | 1 | 1% |
| Unknown | 65 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 21% |
| Student > Ph. D. Student | 14 | 19% |
| Student > Master | 11 | 15% |
| Student > Bachelor | 6 | 8% |
| Professor > Associate Professor | 5 | 7% |
| Other | 14 | 19% |
| Unknown | 7 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 29% |
| Medicine and Dentistry | 16 | 22% |
| Biochemistry, Genetics and Molecular Biology | 10 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Neuroscience | 3 | 4% |
| Other | 9 | 13% |
| Unknown | 10 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2016.
All research outputs
#7,451,942
of 22,782,096 outputs
Outputs from BMC Neuroscience
#374
of 1,243 outputs
Outputs of similar age
#20,470
of 59,073 outputs
Outputs of similar age from BMC Neuroscience
#2
of 4 outputs
Altmetric has tracked 22,782,096 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,243 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 59,073 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.