Title |
microRNAs in viral oncogenesis
|
---|---|
Published in |
Retrovirology, November 2007
|
DOI | 10.1186/1742-4690-4-82 |
Pubmed ID | |
Authors |
Vinod Scaria, Vaibhav Jadhav |
Abstract |
MicroRNAs are a recently discovered class of small noncoding functional RNAs. These molecules mediate post-transcriptional regulation of gene expression in a sequence specific manner. MicroRNAs are now known to be key players in a variety of biological processes and have been shown to be deregulated in a number of cancers. The discovery of viral encoded microRNAs, especially from a family of oncogenic viruses, has attracted immense attention towards the possibility of microRNAs as critical modulators of viral oncogenesis. The host-virus crosstalk mediated by microRNAs, messenger RNAs and proteins, is complex and involves the different cellular regulatory layers. In this commentary, we describe models of microRNA mediated viral oncogenesis. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 6% |
Turkey | 1 | 2% |
Chile | 1 | 2% |
Kenya | 1 | 2% |
India | 1 | 2% |
Canada | 1 | 2% |
Italy | 1 | 2% |
Mexico | 1 | 2% |
Guatemala | 1 | 2% |
Other | 2 | 3% |
Unknown | 50 | 78% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 31% |
Student > Ph. D. Student | 15 | 23% |
Student > Master | 6 | 9% |
Professor | 4 | 6% |
Other | 4 | 6% |
Other | 13 | 20% |
Unknown | 2 | 3% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 36 | 56% |
Biochemistry, Genetics and Molecular Biology | 12 | 19% |
Medicine and Dentistry | 6 | 9% |
Computer Science | 3 | 5% |
Immunology and Microbiology | 2 | 3% |
Other | 2 | 3% |
Unknown | 3 | 5% |