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Molecular ageing in progeroid syndromes: Hutchinson-Gilford progeria syndrome as a model

Overview of attention for article published in Immunity & Ageing, April 2009
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16 Wikipedia pages

Citations

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26 Dimensions

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169 Mendeley
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2 CiteULike
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Title
Molecular ageing in progeroid syndromes: Hutchinson-Gilford progeria syndrome as a model
Published in
Immunity & Ageing, April 2009
DOI 10.1186/1742-4933-6-4
Pubmed ID
Authors

Henrique Douglas M Coutinho, Vivyanne S Falcão-Silva, Gregório Fernandes Gonçalves, Raphael Batista da Nóbrega

Abstract

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder that belongs to a group of conditions called laminopathies which affect nuclear lamins. Mutations in two genes, LMNA and ZMPSTE24, have been found in patients with HGPS. The p.G608G LMNA mutation is the most commonly reported mutation. The aim of this work was to compile a comprehensive literature review of the clinical features and genetic mutations and mechanisms of this syndrome as a contribution to health care workers. This review shows the necessity of a more detailed clinical identification of Hutchinson-Gilford progeria syndrome and the need for more studies on the pharmacologic and pharmacogenomic approach to this syndrome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 1%
France 1 <1%
Brazil 1 <1%
United Kingdom 1 <1%
Mexico 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 161 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 45 27%
Student > Ph. D. Student 30 18%
Student > Master 23 14%
Researcher 14 8%
Student > Postgraduate 8 5%
Other 21 12%
Unknown 28 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 55 33%
Agricultural and Biological Sciences 51 30%
Medicine and Dentistry 9 5%
Engineering 4 2%
Chemistry 4 2%
Other 11 7%
Unknown 35 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2023.
All research outputs
#7,756,853
of 23,578,918 outputs
Outputs from Immunity & Ageing
#166
of 386 outputs
Outputs of similar age
#33,273
of 94,574 outputs
Outputs of similar age from Immunity & Ageing
#2
of 2 outputs
Altmetric has tracked 23,578,918 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 386 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,574 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.