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Mendeley readers
Attention Score in Context
| Title |
Perilesional edema in radiation necrosis reflects axonal degeneration
|
|---|---|
| Published in |
Radiation Oncology, January 2015
|
| DOI | 10.1186/s13014-015-0335-6 |
| Pubmed ID | |
| Authors |
Carlos J Perez-Torres, Liya Yuan, Robert E Schmidt, Keith M Rich, Joseph JH Ackerman, Joel R Garbow |
| Abstract |
BackgroundRecently, we characterized a Gamma Knife® radiation necrosis mouse model with various magnetic resonance imaging (MRI) protocols to identify biomarkers useful in differentiation from tumors. Though the irradiation was focal to one hemisphere, a contralateral injury was observed that appeared to be localized in the white matter only. Interestingly, this injury was identifiable in T2-weighted images, apparent diffusion coefficient (ADC), and magnetization transfer ratio (MTR) maps, but not on post-contrast T1-weighted images. This observation of edema independent of vascular changes is akin to the perilesional edema seen in clinical radiation necrosis.FindingsThe pathology underlying the observed white-matter MRI changes was explored by performing immunohistochemistry for healthy axons and myelin. The presence of both healthy axons and myelin was reduced in the contralateral white-matter lesion.ConclusionsBased on our immunohistochemical findings, the contralateral white-matter injury is most likely due to axonal degeneration. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 25% |
| Spain | 1 | 25% |
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 4% |
| Unknown | 25 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 23% |
| Researcher | 4 | 15% |
| Student > Ph. D. Student | 4 | 15% |
| Professor > Associate Professor | 3 | 12% |
| Other | 2 | 8% |
| Other | 4 | 15% |
| Unknown | 3 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 23% |
| Chemistry | 5 | 19% |
| Physics and Astronomy | 4 | 15% |
| Neuroscience | 3 | 12% |
| Biochemistry, Genetics and Molecular Biology | 2 | 8% |
| Other | 3 | 12% |
| Unknown | 3 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2016.
All research outputs
#12,912,597
of 22,783,848 outputs
Outputs from Radiation Oncology
#556
of 2,052 outputs
Outputs of similar age
#165,179
of 353,087 outputs
Outputs of similar age from Radiation Oncology
#27
of 74 outputs
Altmetric has tracked 22,783,848 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,087 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.