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Incidentally diagnosed melorheostosis of upper limb: case report

Overview of attention for article published in BMC Musculoskeletal Disorders, January 2015
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Title
Incidentally diagnosed melorheostosis of upper limb: case report
Published in
BMC Musculoskeletal Disorders, January 2015
DOI 10.1186/s12891-015-0455-z
Pubmed ID
Authors

Vaclav Vyskocil, Karel Koudela, Tomas Pavelka, Kristyna Stajdlova, David Suchy

Abstract

BackgroundMelorheostosis is quite a rare bone disease with still unclear ethiology. Although multifocal affection is highly debilitating with unfavorable prognosis, there is no clear consensus about therapeutical approach. There is still insufficient evidence in the literature for almost a century after the first description.Affected bone has a typical appearance of melting wax. Diagnosis is usually incidental with pain as a leading symptom. Diagnosis itself is relatively easy, routine X-ray examination is sufficient. Even though it could be easily overlooked and mistaken with other diseases. Melorheostosis is incurable, the therapy is mostly focused on maintaining patient quality of life.Presented case is unique in terms of extent of the affection (index finger, metacarp shaft, carpal bones, forearm, humerus and whole scapula) in combination with osteopoikilotic islands in other 3 regions (vertebrae, manubrium sterni and left collar bone). Currently there is only one such a case published in the literature (Campbell), but without osteopoikilotic islands.Case presentationMelorheostosis was diagnosed in 26-year old female after injury as an incidental finding. This was quite surprising as the patient already suffered by limited movement in the upper limb and pain before the injury. Detailed examination were performed to confirm the diagnosis, no family history was found. Pharmacotherapy with bisphosphonates, non-steroidal antirheumatics and vasodilatans/rheologic drugs seemed to be effective to maintain the relatively good quality of patient life and good performance in daily routine. Questionable is further development of patient performance status and sustainability of conservative treatment in the long term follow up.ConclusionConservative treatment with bisphopshonates and COX-2 inhibitors in combination with naftidrofuryl can delay surgery solution.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 33%
Student > Master 4 19%
Student > Bachelor 4 19%
Student > Ph. D. Student 1 5%
Other 1 5%
Other 2 10%
Unknown 2 10%
Readers by discipline Count As %
Medicine and Dentistry 9 43%
Nursing and Health Professions 3 14%
Decision Sciences 1 5%
Social Sciences 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Other 1 5%
Unknown 5 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2015.
All research outputs
#3,343,339
of 5,036,026 outputs
Outputs from BMC Musculoskeletal Disorders
#1,281
of 1,695 outputs
Outputs of similar age
#115,291
of 179,749 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#41
of 49 outputs
Altmetric has tracked 5,036,026 research outputs across all sources so far. This one is in the 29th percentile – i.e., 29% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,695 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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