Title |
Models for synthetic biology
|
---|---|
Published in |
BMC Systems Biology, November 2007
|
DOI | 10.1186/1752-0509-1-47 |
Pubmed ID | |
Authors |
Yiannis N Kaznessis |
Abstract |
Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior. The objective is the design and construction of new biological devices and systems to deliver useful applications. Numerous synthetic gene circuits have been created in the past decade, including bistable switches, oscillators, and logic gates, and possible applications abound, including biofuels, detectors for biochemical and chemical weapons, disease diagnosis, and gene therapies. More than fifty years after the discovery of the molecular structure of DNA, molecular biology is mature enough for real quantification that is useful for biological engineering applications, similar to the revolution in modeling in chemistry in the 1950s. With the excitement that synthetic biology is generating, the engineering and biological science communities appear remarkably willing to cross disciplinary boundaries toward a common goal. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 8 | 3% |
Mexico | 5 | 2% |
United Kingdom | 5 | 2% |
France | 2 | <1% |
Germany | 2 | <1% |
Portugal | 2 | <1% |
Austria | 1 | <1% |
Brazil | 1 | <1% |
Indonesia | 1 | <1% |
Other | 7 | 3% |
Unknown | 207 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 61 | 25% |
Researcher | 51 | 21% |
Student > Bachelor | 30 | 12% |
Student > Master | 26 | 11% |
Other | 17 | 7% |
Other | 35 | 15% |
Unknown | 21 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 100 | 41% |
Biochemistry, Genetics and Molecular Biology | 31 | 13% |
Engineering | 27 | 11% |
Computer Science | 21 | 9% |
Social Sciences | 8 | 3% |
Other | 27 | 11% |
Unknown | 27 | 11% |