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Experimental evaluation of the relationship between lethal or non-lethal virulence and transmission success in malaria parasite infections

Overview of attention for article published in BMC Ecology and Evolution, September 2004
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Title
Experimental evaluation of the relationship between lethal or non-lethal virulence and transmission success in malaria parasite infections
Published in
BMC Ecology and Evolution, September 2004
DOI 10.1186/1471-2148-4-30
Pubmed ID
Authors

REL Paul, T Lafond, CDM Müller-Graf, S Nithiuthai, PT Brey, JC Koella

Abstract

Evolutionary theory suggests that the selection pressure on parasites to maximize their transmission determines their optimal host exploitation strategies and thus their virulence. Establishing the adaptive basis to parasite life history traits has important consequences for predicting parasite responses to public health interventions. In this study we examine the extent to which malaria parasites conform to the predicted adaptive trade-off between transmission and virulence, as defined by mortality. The majority of natural infections, however, result in sub-lethal virulent effects (e.g. anaemia) and are often composed of many strains. Both sub-lethal effects and pathogen population structure have been theoretically shown to have important consequences for virulence evolution. Thus, we additionally examine the relationship between anaemia and transmission in single and mixed clone infections.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 2 2%
Brazil 1 1%
Portugal 1 1%
France 1 1%
Lithuania 1 1%
Unknown 83 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 22%
Student > Ph. D. Student 17 19%
Student > Master 14 15%
Student > Bachelor 11 12%
Professor 7 8%
Other 18 20%
Unknown 4 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 52 57%
Biochemistry, Genetics and Molecular Biology 6 7%
Environmental Science 5 5%
Immunology and Microbiology 4 4%
Medicine and Dentistry 3 3%
Other 13 14%
Unknown 8 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2021.
All research outputs
#8,543,833
of 25,394,764 outputs
Outputs from BMC Ecology and Evolution
#1,997
of 3,714 outputs
Outputs of similar age
#23,019
of 70,199 outputs
Outputs of similar age from BMC Ecology and Evolution
#7
of 13 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 70,199 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.