Title |
Chronic Granulomatous Disease; fundamental stages in our understanding of CGD
|
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Published in |
Medical Immunology, September 2006
|
DOI | 10.1186/1476-9433-5-4 |
Pubmed ID | |
Authors |
Tracy Assari |
Abstract |
It has been 50 years since chronic granulomatous disease was first reported as a disease which fatally affected the ability of children to survive infections. Various milestone discoveries from the insufficient ability of patients' leucocytes to destroy microbial particles to the underlying genetic predispositions through which the disease is inherited have had important consequences. Longterm antibiotic prophylaxis has helped to fight infections associated with chronic granulomatous disease while the steady progress in bone marrow transplantation and the prospect of gene therapy are hailed as long awaited permanent treatment options. This review unearths the important findings by scientists that have led to our current understanding of the disease. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Chile | 1 | 1% |
Mexico | 1 | 1% |
Argentina | 1 | 1% |
Unknown | 75 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 20% |
Student > Ph. D. Student | 12 | 15% |
Student > Bachelor | 11 | 14% |
Researcher | 11 | 14% |
Other | 8 | 10% |
Other | 14 | 18% |
Unknown | 7 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 28% |
Medicine and Dentistry | 21 | 27% |
Biochemistry, Genetics and Molecular Biology | 12 | 15% |
Immunology and Microbiology | 4 | 5% |
Chemistry | 3 | 4% |
Other | 9 | 11% |
Unknown | 8 | 10% |