Title |
Designer synthetic media for studying microbial-catalyzed biofuel production
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Published in |
Biotechnology for Biofuels and Bioproducts, January 2015
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DOI | 10.1186/s13068-014-0179-6 |
Pubmed ID | |
Authors |
Xiaoyu Tang, Leonardo da Costa Sousa, Mingjie Jin, Shishir PS Chundawat, Charles Kevin Chambliss, Ming W Lau, Zeyi Xiao, Bruce E Dale, Venkatesh Balan |
Abstract |
The fermentation inhibition of yeast or bacteria by lignocellulose-derived degradation products, during hexose/pentose co-fermentation, is a major bottleneck for cost-effective lignocellulosic biorefineries. To engineer microbial strains for improved performance, it is critical to understand the mechanisms of inhibition that affect fermentative organisms in the presence of major components of a lignocellulosic hydrolysate. The development of a synthetic lignocellulosic hydrolysate (SH) media with a composition similar to the actual biomass hydrolysate will be an important advancement to facilitate these studies. In this work, we characterized the nutrients and plant-derived decomposition products present in AFEX™ pretreated corn stover hydrolysate (ACH). The SH was formulated based on the ACH composition and was further used to evaluate the inhibitory effects of various families of decomposition products during Saccharomyces cerevisiae 424A (LNH-ST) fermentation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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India | 1 | 50% |
France | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Indonesia | 1 | 1% |
United States | 1 | 1% |
Unknown | 83 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 16 | 19% |
Researcher | 15 | 18% |
Student > Bachelor | 10 | 12% |
Student > Master | 9 | 11% |
Professor > Associate Professor | 8 | 9% |
Other | 15 | 18% |
Unknown | 12 | 14% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 26 | 31% |
Biochemistry, Genetics and Molecular Biology | 13 | 15% |
Chemical Engineering | 10 | 12% |
Engineering | 9 | 11% |
Chemistry | 3 | 4% |
Other | 8 | 9% |
Unknown | 16 | 19% |