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Heteromers of amyloid precursor protein in cerebrospinal fluid.

Overview of attention for article published in Molecular Neurodegeneration, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
3 news outlets
twitter
2 X users
facebook
2 Facebook pages

Citations

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22 Dimensions

Readers on

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50 Mendeley
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Title
Heteromers of amyloid precursor protein in cerebrospinal fluid.
Published in
Molecular Neurodegeneration, January 2015
DOI 10.1186/1750-1326-10-2
Pubmed ID
Authors

Cuchillo-Ibañez I, Lopez-Font I, Boix-Amorós A, Brinkmalm G, Blennow K, Molinuevo JL, Sáez-Valero J

Abstract

Soluble fragments of the amyloid precursor protein (APP) generated by α- and β-secretases, sAPPα and sAPPβ, have been postulated as promising new cerebrospinal fluid (CSF) biomarkers for the clinical diagnosis of Alzheimer's disease (AD). However, the capacity of these soluble proteins to assemble has not been explored and could be relevant. Our aim is to characterize possible sAPP oligomers that could contribute to the quantification of sAPPα and sAPPβ in CSF by ELISA, as well as to characterize the possible presence of soluble full-length APP (sAPPf).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Russia 1 2%
Unknown 48 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 24%
Researcher 10 20%
Student > Master 8 16%
Student > Bachelor 4 8%
Student > Doctoral Student 2 4%
Other 5 10%
Unknown 9 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 26%
Biochemistry, Genetics and Molecular Biology 7 14%
Neuroscience 5 10%
Medicine and Dentistry 4 8%
Nursing and Health Professions 1 2%
Other 5 10%
Unknown 15 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2015.
All research outputs
#1,277,936
of 22,783,848 outputs
Outputs from Molecular Neurodegeneration
#80
of 847 outputs
Outputs of similar age
#18,818
of 352,303 outputs
Outputs of similar age from Molecular Neurodegeneration
#3
of 15 outputs
Altmetric has tracked 22,783,848 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 847 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,303 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.