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Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats

Overview of attention for article published in BMC Veterinary Research, February 2018
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Title
Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats
Published in
BMC Veterinary Research, February 2018
DOI 10.1186/s12917-018-1356-9
Pubmed ID
Authors

Andrea Balboni, Francesca Bassi, Stefano De Arcangeli, Rosanna Zobba, Carla Dedola, Alberto Alberti, Mara Battilani

Abstract

Cats are susceptible to feline panleukopenia virus (FPV) and canine parvovirus (CPV) variants 2a, 2b and 2c. Detection of FPV and CPV variants in apparently healthy cats and their persistence in white blood cells (WBC) and other tissues when neutralising antibodies are simultaneously present, suggest that parvovirus may persist long-term in the tissues of cats post-infection without causing clinical signs. The aim of this study was to screen a population of 54 cats from Sardinia (Italy) for the presence of both FPV and CPV DNA within buffy coat samples using polymerase chain reaction (PCR). The DNA viral load, genetic diversity, phylogeny and antibody titres against parvoviruses were investigated in the positive cats. Carnivore protoparvovirus 1 DNA was detected in nine cats (16.7%). Viral DNA was reassembled to FPV in four cats and to CPV (CPV-2b and 2c) in four cats; one subject showed an unusually high genetic complexity with mixed infection involving FPV and CPV-2c. Antibodies against parvovirus were detected in all subjects which tested positive to DNA parvoviruses. The identification of FPV and CPV DNA in the WBC of asymptomatic cats, despite the presence of specific antibodies against parvoviruses, and the high genetic heterogeneity detected in one sample, confirmed the relevant epidemiological role of cats in parvovirus infection.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 21%
Student > Bachelor 4 12%
Researcher 3 9%
Student > Ph. D. Student 3 9%
Student > Doctoral Student 2 6%
Other 2 6%
Unknown 12 36%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 12 36%
Agricultural and Biological Sciences 4 12%
Biochemistry, Genetics and Molecular Biology 1 3%
Computer Science 1 3%
Immunology and Microbiology 1 3%
Other 0 0%
Unknown 14 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2018.
All research outputs
#13,579,722
of 23,020,670 outputs
Outputs from BMC Veterinary Research
#944
of 3,065 outputs
Outputs of similar age
#218,780
of 437,326 outputs
Outputs of similar age from BMC Veterinary Research
#36
of 95 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,065 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,326 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.