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Mendeley readers
Attention Score in Context
| Title |
Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease
|
|---|---|
| Published in |
BMC Neuroscience, June 2009
|
| DOI | 10.1186/1471-2202-10-64 |
| Pubmed ID | |
| Authors |
Manoj Kumar Jaiswal, Wolf-Dieter Zech, Miriam Goos, Christine Leutbecher, Alberto Ferri, Annette Zippelius, Maria Teresa Carrì, Roland Nau, Bernhard U Keller |
| Abstract |
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective loss of motor neurons (MN) in the brain stem and spinal cord. Intracellular disruptions of cytosolic and mitochondrial calcium have been associated with selective MN degeneration, but the underlying mechanisms are not well understood. The present evidence supports a hypothesis that mitochondria are a target of mutant SOD1-mediated toxicity in familial amyotrophic lateral sclerosis (fALS) and intracellular alterations of cytosolic and mitochondrial calcium might aggravate the course of this neurodegenerative disease. In this study, we used a fluorescence charged cool device (CCD) imaging system to separate and simultaneously monitor cytosolic and mitochondrial calcium concentrations in individual cells in an established cellular model of ALS. |
Mendeley readers
The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 3% |
| Korea, Republic of | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 116 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 20% |
| Student > Bachelor | 19 | 16% |
| Student > Master | 17 | 14% |
| Researcher | 11 | 9% |
| Student > Doctoral Student | 6 | 5% |
| Other | 20 | 16% |
| Unknown | 25 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 35 | 29% |
| Neuroscience | 20 | 16% |
| Medicine and Dentistry | 14 | 11% |
| Biochemistry, Genetics and Molecular Biology | 13 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 12 | 10% |
| Unknown | 25 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2021.
All research outputs
#7,453,126
of 22,785,242 outputs
Outputs from BMC Neuroscience
#374
of 1,244 outputs
Outputs of similar age
#37,558
of 111,409 outputs
Outputs of similar age from BMC Neuroscience
#10
of 23 outputs
Altmetric has tracked 22,785,242 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,244 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,409 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.