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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hepcidin, an emerging and important player in brain iron homeostasis
|
|---|---|
| Published in |
Journal of Translational Medicine, February 2018
|
| DOI | 10.1186/s12967-018-1399-5 |
| Pubmed ID | |
| Authors |
Driton Vela |
| Abstract |
Hepcidin is emerging as a new important factor in brain iron homeostasis. Studies suggest that there are two sources of hepcidin in the brain; one is local and the other comes from the circulation. Little is known about the molecular mediators of local hepcidin expression, but inflammation and iron-load have been shown to induce hepcidin expression in the brain. The most important source of hepcidin in the brain are glial cells. Role of hepcidin in brain functions has been observed during neuronal iron-load and brain hemorrhage, where secretion of abundant hepcidin is related with the severity of brain damage. This damage can be reversed by blocking systemic and local hepcidin secretion. Studies have yet to unveil its role in other brain conditions, but the rationale exists, since these conditions are characterized by overexpression of the factors that stimulate brain hepcidin expression, such as inflammation, hypoxia and iron-overload. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 148 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 17% |
| Student > Master | 22 | 15% |
| Student > Ph. D. Student | 21 | 14% |
| Student > Bachelor | 7 | 5% |
| Other | 7 | 5% |
| Other | 21 | 14% |
| Unknown | 45 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 14% |
| Medicine and Dentistry | 21 | 14% |
| Neuroscience | 16 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 5% |
| Chemistry | 7 | 5% |
| Other | 28 | 19% |
| Unknown | 47 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2019.
All research outputs
#17,929,042
of 23,020,670 outputs
Outputs from Journal of Translational Medicine
#2,768
of 4,027 outputs
Outputs of similar age
#308,282
of 437,836 outputs
Outputs of similar age from Journal of Translational Medicine
#79
of 86 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,027 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.