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Mendeley readers
Attention Score in Context
| Title |
Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort
|
|---|---|
| Published in |
BMC Gastroenterology, January 2009
|
| DOI | 10.1186/1471-230x-9-6 |
| Pubmed ID | |
| Authors |
Gerard Clarke, Peter Fitzgerald, John F Cryan, Eugene M Cassidy, Eamonn M Quigley, Timothy G Dinan |
| Abstract |
Irritable bowel syndrome (IBS) is a common disorder that affects 10-15% of the population. Although characterised by a lack of reliable biological markers, the disease state is increasingly viewed as a disorder of the brain-gut axis. In particular, accumulating evidence points to the involvement of both the central and peripheral serotonergic systems in disease symptomatology. Furthermore, altered tryptophan metabolism and indoleamine 2,3-dioxygenase (IDO) activity are hallmarks of many stress-related disorders. The kynurenine pathway of tryptophan degradation may serve to link these findings to the low level immune activation recently described in IBS. In this study, we investigated tryptophan degradation in a male IBS cohort (n = 10) and control subjects (n = 26). |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Ireland | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 111 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 17% |
| Researcher | 20 | 17% |
| Student > Bachelor | 16 | 14% |
| Student > Master | 10 | 9% |
| Other | 6 | 5% |
| Other | 18 | 16% |
| Unknown | 25 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 22% |
| Medicine and Dentistry | 24 | 21% |
| Neuroscience | 10 | 9% |
| Psychology | 5 | 4% |
| Immunology and Microbiology | 4 | 3% |
| Other | 20 | 17% |
| Unknown | 27 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2015.
All research outputs
#7,208,880
of 22,785,242 outputs
Outputs from BMC Gastroenterology
#451
of 1,743 outputs
Outputs of similar age
#48,332
of 170,351 outputs
Outputs of similar age from BMC Gastroenterology
#4
of 7 outputs
Altmetric has tracked 22,785,242 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,743 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,351 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.