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Idiopathic pulmonary fibrosis

Overview of attention for article published in Orphanet Journal of Rare Diseases, March 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
2 news outlets
twitter
2 tweeters
patent
3 patents
facebook
1 Facebook page
wikipedia
4 Wikipedia pages
googleplus
1 Google+ user

Citations

dimensions_citation
280 Dimensions

Readers on

mendeley
292 Mendeley
citeulike
1 CiteULike
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Title
Idiopathic pulmonary fibrosis
Published in
Orphanet Journal of Rare Diseases, March 2008
DOI 10.1186/1750-1172-3-8
Pubmed ID
Authors

Eric B Meltzer, Paul W Noble

Abstract

Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation. IPF is a rare disease which affects approximately 5 million persons worldwide. The prevalence is estimated to be slightly greater in men (20.2/100,000) than in women (13.2/100,000). The mean age at presentation is 66 years. IPF initially manifests with symptoms of exercise-induced breathless and dry coughing. Auscultation of the lungs reveals early inspiratory crackles, predominantly located in the lower posterior lung zones upon physical exam. Clubbing is found in approximately 50% of IPF patients. Cor pulmonale develops in association with end-stage disease. In that case, classic signs of right heart failure may be present. Etiology remains incompletely understood. Some environmental factors may be associated with IPF (cigarette smoking, exposure to silica and livestock). IPF is recognized on high-resolution computed tomography by peripheral, subpleural lower lobe reticular opacities in association with subpleural honeycomb changes. IPF is associated with a pathological lesion known as usual interstitial pneumonia (UIP). The UIP pattern consists of normal lung alternating with patches of dense fibrosis, taking the form of collagen sheets. The diagnosis of IPF requires correlation of the clinical setting with radiographic images and a lung biopsy. In the absence of lung biopsy, the diagnosis of IPF can be made by defined clinical criteria that were published in guidelines endorsed by several professional societies. Differential diagnosis includes other idiopathic interstitial pneumonia, connective tissue diseases (systemic sclerosis, polymyositis, rheumatoid arthritis), forme fruste of autoimmune disorders, chronic hypersensitivity pneumonitis and other environmental (sometimes occupational) exposures. IPF is typically progressive and leads to significant disability. The median survival is 2 to 5 years from the time of diagnosis. Medical therapy is ineffective in the treatment of IPF. New molecular therapeutic targets have been identified and several clinical trials are investigating the efficacy of novel medication. Meanwhile, pulmonary transplantation remains a viable option for patients with IPF. It is expected that, during the next decade, considerable progress will be made toward the understanding and treatment of this devastating illness.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 292 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Germany 2 <1%
Japan 2 <1%
India 1 <1%
Brazil 1 <1%
Denmark 1 <1%
Italy 1 <1%
Colombia 1 <1%
Philippines 1 <1%
Other 0 0%
Unknown 280 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 51 17%
Student > Ph. D. Student 47 16%
Student > Bachelor 47 16%
Researcher 46 16%
Other 21 7%
Other 42 14%
Unknown 38 13%
Readers by discipline Count As %
Medicine and Dentistry 110 38%
Agricultural and Biological Sciences 49 17%
Biochemistry, Genetics and Molecular Biology 28 10%
Chemistry 19 7%
Pharmacology, Toxicology and Pharmaceutical Science 9 3%
Other 38 13%
Unknown 39 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2021.
All research outputs
#1,100,708
of 18,203,597 outputs
Outputs from Orphanet Journal of Rare Diseases
#98
of 1,947 outputs
Outputs of similar age
#19,205
of 299,928 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#2
of 27 outputs
Altmetric has tracked 18,203,597 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,947 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,928 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.