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Proteome-wide comparison between the amino acid composition of domains and linkers

Overview of attention for article published in BMC Research Notes, February 2018
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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8 X users
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1 Google+ user

Citations

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60 Mendeley
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Title
Proteome-wide comparison between the amino acid composition of domains and linkers
Published in
BMC Research Notes, February 2018
DOI 10.1186/s13104-018-3221-0
Pubmed ID
Authors

Daniel Brüne, Miguel A. Andrade-Navarro, Pablo Mier

Abstract

Amino acid composition is a sequence feature that has been extensively used to characterize proteomes of many species and protein families. Yet the analysis of amino acid composition of protein domains and the linkers connecting them has received less attention. Here, we perform both a comprehensive full-proteome amino acid composition analysis and a similar analysis focusing on domains and linkers, to uncover domain- or linker-specific differential amino acid usage patterns. The amino acid composition in the 38 proteomes studied showcase the greater variability found in archaea and bacteria species compared to eukaryotes. When focusing on domains and linkers, we describe the preferential use of polar residues in linkers and hydrophobic residues in domains. To let any user perform this analysis on a given domain (or set of them), we developed a dedicated R script called RACCOON, which can be easily used and can provide interesting insights into the compositional differences between a domain and its surrounding linkers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 15%
Researcher 8 13%
Professor 6 10%
Student > Master 6 10%
Student > Bachelor 5 8%
Other 14 23%
Unknown 12 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 33%
Chemistry 8 13%
Agricultural and Biological Sciences 4 7%
Chemical Engineering 1 2%
Unspecified 1 2%
Other 7 12%
Unknown 19 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#5,975,501
of 23,649,378 outputs
Outputs from BMC Research Notes
#862
of 4,302 outputs
Outputs of similar age
#119,531
of 445,393 outputs
Outputs of similar age from BMC Research Notes
#24
of 118 outputs
Altmetric has tracked 23,649,378 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,302 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 445,393 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.