Title |
Evaluation and optimization of a commercial enzyme linked immunosorbent assay for detection of Chlamydophila pneumoniaeIgA antibodies
|
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Published in |
BMC Infectious Diseases, July 2008
|
DOI | 10.1186/1471-2334-8-98 |
Pubmed ID | |
Authors |
Olfa Frikha-Gargouri, Radhouane Gdoura, Abir Znazen, Nozha Ben Arab, Jalel Gargouri, Mounir Ben Jemaa, Adnene Hammami |
Abstract |
Serologic diagnosis of Chlamydophila pneumoniae (Cpn) infection routinely involves assays for the presence of IgG and IgM antibodies to Cpn. Although IgA antibodies to Cpn have been found to be of interest in the diagnosis of chronic infections, their significance in serological diagnosis remains unclear. The microimmunofluorescence (MIF) test is the current method for the measurement of Cpn antibodies. While commercial enzyme linked immunosorbent assays (ELISA) have been developed, they have not been fully validated. We therefore evaluated and optimized a commercial ELISA kit, the SeroCP IgA test, for the detection of Cpn IgA antibodies. |
Mendeley readers
Geographical breakdown
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 1 | 8% |
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