You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of the T and B lymphocytes in pathogenesis of autoimmune thyroid diseases
|
|---|---|
| Published in |
Thyroid Research, February 2018
|
| DOI | 10.1186/s13044-018-0046-9 |
| Pubmed ID | |
| Authors |
Marta Rydzewska, Michał Jaromin, Izabela Elżbieta Pasierowska, Karlina Stożek, Artur Bossowski |
| Abstract |
Autoimmune thyroid disorders (AITD) broadly include Graves' disease and Hashimoto's thyroiditis which are the most common causes of thyroid gland dysfunctions. These disorders develop due to complex interactions between environmental and genetic factors and are characterized by reactivity to self-thyroid antigens due to autoreactive lymphocytes escaping tolerance. Both cell-mediated and humoral responses lead to tissue injury in autoimmune thyroid disease. The differentiation of CD4+ cells in the specific setting of immune mediators (for example cytokines, chemokines) results in differentiation of various T cell subsets. T cell identification has shown a mixed pattern of cytokine production indicating that both subtypes of T helper, Th1 and Th2, responses are involved in all types of AITD. Furthermore, recent studies described T cell subtypes Th17 and Treg which also play an essential role in pathogenesis of AITD. This review will focus on the role of the T regulatory (Treg) and T helper (Th) (especially Th17) lymphocytes, and also of B lymphocytes in AITD pathogenesis. However, we have much more to learn about cellular mechanisms and interactions in AITD before we can develop complete understanding of AITD pathophysiology. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 182 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 182 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 24 | 13% |
| Researcher | 23 | 13% |
| Student > Bachelor | 22 | 12% |
| Student > Ph. D. Student | 10 | 5% |
| Student > Postgraduate | 8 | 4% |
| Other | 19 | 10% |
| Unknown | 76 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 35 | 19% |
| Biochemistry, Genetics and Molecular Biology | 16 | 9% |
| Immunology and Microbiology | 14 | 8% |
| Nursing and Health Professions | 10 | 5% |
| Agricultural and Biological Sciences | 9 | 5% |
| Other | 19 | 10% |
| Unknown | 79 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2019.
All research outputs
#20,278,732
of 25,789,020 outputs
Outputs from Thyroid Research
#157
of 219 outputs
Outputs of similar age
#333,031
of 458,038 outputs
Outputs of similar age from Thyroid Research
#2
of 2 outputs
Altmetric has tracked 25,789,020 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 219 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 458,038 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.