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Clinical evaluation of two different protein content formulas fed to full-term healthy infants: a randomized controlled trial

Overview of attention for article published in BMC Pediatrics, February 2018
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Title
Clinical evaluation of two different protein content formulas fed to full-term healthy infants: a randomized controlled trial
Published in
BMC Pediatrics, February 2018
DOI 10.1186/s12887-018-1046-6
Pubmed ID
Authors

Nadia Liotto, Anna Orsi, Camilla Menis, Pasqua Piemontese, Laura Morlacchi, Chiara Cristiana Condello, Maria Lorella Giannì, Paola Roggero, Fabio Mosca

Abstract

A high early protein intake is associated with rapid postnatal weight gain and altered body composition. We aimed to evaluate the safety of a low-protein formula in healthy full-term infants. A randomized controlled trial was conducted. A total of 118 infants were randomized to receive two different protein content formulas (formula A or formula B (protein content: 1.2 vs. 1.7 g/100 mL, respectively)) for the first 4 months of life. Anthropometry and body composition by air displacement plethysmography were assessed at enrolment and at two and 4 months. The reference group comprised 50 healthy, exclusively breastfed, full-term infants. Weight gain (g/day) throughout the study was similar between the formula groups (32.5 ± 6.1 vs. 32.8 ± 6.8) and in the reference group (30.4 ± 5.4). The formula groups showed similar body composition but a different fat-free mass content from breastfed infants at two and 4 months. However, the formula A group showed a fat-free mass increase more similar to that of the breastfed infants. The occurrence of gastrointestinal symptoms or adverse events was similar between the formula groups. Feeding a low-protein content formula appears to be safe and to promote adequate growth, although determination of the long-term effect on body composition requires further study. The present study was retrospectively registered in ClinicalTrials.gov (trial number: NCT03035721 on January 18, 2017).

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 68 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 15%
Student > Master 7 10%
Student > Ph. D. Student 6 9%
Lecturer 4 6%
Researcher 4 6%
Other 12 18%
Unknown 25 37%
Readers by discipline Count As %
Medicine and Dentistry 14 21%
Nursing and Health Professions 10 15%
Biochemistry, Genetics and Molecular Biology 5 7%
Unspecified 2 3%
Agricultural and Biological Sciences 2 3%
Other 8 12%
Unknown 27 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2019.
All research outputs
#15,867,545
of 23,577,761 outputs
Outputs from BMC Pediatrics
#2,103
of 3,111 outputs
Outputs of similar age
#277,206
of 448,832 outputs
Outputs of similar age from BMC Pediatrics
#65
of 90 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,111 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,832 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.