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Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients

Overview of attention for article published in BMC Pulmonary Medicine, February 2018
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  • Good Attention Score compared to outputs of the same age (69th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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Citations

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Title
Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients
Published in
BMC Pulmonary Medicine, February 2018
DOI 10.1186/s12890-018-0594-8
Pubmed ID
Authors

Bryan A. Garcia, Jacque L. Carden, Dana L. Goodwin, Tim A. Smith, Amit Gaggar, Kevin Leon, Veena B. Antony, Steven M. Rowe, George M. Solomon

Abstract

Infection with Burkholderia cepacia complex (Bcc) results in a heterogeneous clinical course ranging from asymptomatic colonization of the airways to fulminant respiratory failure in patients with cystic fibrosis (CF). Early eradication of Pseudomonas aeruginosa improves clinical outcomes. The efficacy and clinical outcomes following implementation of an eradication protocol for Bcc are less well understood. We developed and implemented a single center Bcc eradication protocol that included an intensive combination of intravenous, inhaled, and oral antibiotic therapies based on in vitro sensitivities. We conducted a retrospective cohort analysis of clinical outcomes compared to patients with chronic Bcc infection. Six patients were identified as having a newly acquired Bcc colonization and were placed on the eradication protocol. Sequential sputum samples after completion of the protocol demonstrated sustained clearance of Bcc in all patients. Lung function and nutritional status remained stable in the year following eradication. Clearance of Bcc from sputum cultures using a standardized protocol was successful at one year and was associated with clinical stability.

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The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 15%
Researcher 7 13%
Student > Ph. D. Student 4 7%
Other 3 6%
Student > Master 3 6%
Other 8 15%
Unknown 21 39%
Readers by discipline Count As %
Medicine and Dentistry 13 24%
Biochemistry, Genetics and Molecular Biology 6 11%
Immunology and Microbiology 4 7%
Nursing and Health Professions 3 6%
Agricultural and Biological Sciences 3 6%
Other 4 7%
Unknown 21 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2018.
All research outputs
#6,399,517
of 23,306,612 outputs
Outputs from BMC Pulmonary Medicine
#477
of 1,972 outputs
Outputs of similar age
#133,487
of 447,745 outputs
Outputs of similar age from BMC Pulmonary Medicine
#11
of 52 outputs
Altmetric has tracked 23,306,612 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,972 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,745 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.