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Mendeley readers
Attention Score in Context
| Title |
Differential production of superoxide by neuronal mitochondria
|
|---|---|
| Published in |
BMC Neuroscience, January 2008
|
| DOI | 10.1186/1471-2202-9-4 |
| Pubmed ID | |
| Authors |
Mark J Hoegger, Christopher J Lieven, Leonard A Levin |
| Abstract |
Mitochondrial DNA (mtDNA) mutations, which are present in all mitochondria-containing cells, paradoxically cause tissue-specific disease. For example, Leber's hereditary optic neuropathy (LHON) results from one of three point mutations mtDNA coding for complex I components, but is only manifested in retinal ganglion cells (RGCs), a central neuron contained within the retina. Given that RGCs use superoxide for intracellular signaling after axotomy, and that LHON mutations increase superoxide levels in non-RGC transmitochondrial cybrids, we hypothesized that RGCs regulate superoxide levels differently than other neuronal cells. To study this, we compared superoxide production and mitochondrial electron transport chain (METC) components in isolated RGC mitochondria to mitochondria isolated from cerebral cortex and neuroblastoma SK-N-AS cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 4% |
| Unknown | 27 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 32% |
| Student > Bachelor | 3 | 11% |
| Other | 3 | 11% |
| Student > Ph. D. Student | 3 | 11% |
| Student > Master | 2 | 7% |
| Other | 4 | 14% |
| Unknown | 4 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 21% |
| Medicine and Dentistry | 6 | 21% |
| Neuroscience | 5 | 18% |
| Biochemistry, Genetics and Molecular Biology | 3 | 11% |
| Chemical Engineering | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 5 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2020.
All research outputs
#7,453,350
of 22,786,087 outputs
Outputs from BMC Neuroscience
#374
of 1,244 outputs
Outputs of similar age
#41,866
of 156,425 outputs
Outputs of similar age from BMC Neuroscience
#9
of 11 outputs
Altmetric has tracked 22,786,087 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,244 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,425 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.