Title |
Clinical similarities among bradykinin‐mediated and mast cell‐mediated subtypes of non‐hereditary angioedema: a retrospective study
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Published in |
Clinical and Translational Allergy, February 2015
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DOI | 10.1186/s13601-015-0049-8 |
Pubmed ID | |
Authors |
Karlijn J G Schulkes, Mignon T Van den Elzen, Erik C Hack, Henderikus G Otten, Carla A F M Bruijnzeel-Koomen, André C Knulst |
Abstract |
Non-hereditary angioedema (non-HAE) is characterized by local swelling due to self-limiting, subcutaneous or submucosal extravasation of fluid, and can be divided into three subtypes. These subtypes are believed to have different pathophysiological backgrounds and are referred to in recent guidelines as bradykinin-mediated (e.g. caused by angiotensin-converting-enzyme-inhibitors), mast cell-mediated (e.g. angioedema with wheals) or idiopathic (cause unknown). Bradykinin-mediated subtypes are more closely related to hereditary angioedema than the other forms. Because clinical features of these non-HAE subtypes have not been studied in detail, we have looked at the clinical characteristics of symptoms and potential differences in clinical presentation of bradykinin-mediated and mast cell-mediated angioedema (AE) subtypes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 40% |
Austria | 1 | 20% |
Switzerland | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 3 | 60% |
Members of the public | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Turkey | 1 | 3% |
Unknown | 29 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 17% |
Other | 3 | 10% |
Student > Doctoral Student | 3 | 10% |
Researcher | 3 | 10% |
Student > Master | 3 | 10% |
Other | 5 | 17% |
Unknown | 8 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 63% |
Computer Science | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Social Sciences | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 0 | 0% |
Unknown | 7 | 23% |