You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Protein prenyltransferases
|
|---|---|
| Published in |
Genome Biology, April 2003
|
| DOI | 10.1186/gb-2003-4-4-212 |
| Pubmed ID | |
| Authors |
Sebastian Maurer-Stroh, Stefan Washietl, Frank Eisenhaber |
| Abstract |
Three different protein prenyltransferases (farnesyltransferase and geranylgeranyltransferases I and II) catalyze the attachment of prenyl lipid anchors 15 or 20 carbons long to the carboxyl termini of a variety of eukaryotic proteins. Farnesyltransferase and geranylgeranyltransferase I both recognize a 'Ca1a2X' motif on their protein substrates; geranylgeranyltransferase II recognizes a different, non-CaaX motif. Each enzyme has two subunits. The genes encoding CaaX protein prenyltransferases are considerably longer than those encoding non-CaaX subunits, as a result of longer introns. Alternative splice forms are predicted to occur, but the extent to which each splice form is translated and the functions of the different resulting isoforms remain to be established. Farnesyltransferase-inhibitor drugs have been developed as anti-cancer agents and may also be able to treat several other diseases. The effects of these inhibitors are complicated, however, by the overlapping substrate specificities of geranylgeranyltransferase I and farnesyltransferase. |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Mexico | 1 | <1% |
| Trinidad and Tobago | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 126 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 23% |
| Researcher | 24 | 18% |
| Professor | 10 | 8% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 9 | 7% |
| Other | 30 | 23% |
| Unknown | 19 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 47 | 36% |
| Biochemistry, Genetics and Molecular Biology | 27 | 20% |
| Chemistry | 13 | 10% |
| Medicine and Dentistry | 8 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 13 | 10% |
| Unknown | 20 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2010.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from Genome Biology
#3,489
of 4,467 outputs
Outputs of similar age
#20,903
of 63,302 outputs
Outputs of similar age from Genome Biology
#9
of 27 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 63,302 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.