Title |
Effectiveness of compression stockings to prevent the post-thrombotic syndrome (The SOX Trial and Bio-SOX biomarker substudy): a randomized controlled trial
|
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Published in |
BMC Cardiovascular Disorders, July 2007
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DOI | 10.1186/1471-2261-7-21 |
Pubmed ID | |
Authors |
Susan R Kahn, Hadia Shbaklo, Stan Shapiro, Philip S Wells, Michael J Kovacs, Marc A Rodger, David R Anderson, Jeffrey S Ginsberg, Mira Johri, Vicky Tagalakis, the SOX Trial Investigators |
Abstract |
Post thrombotic syndrome (PTS) is a burdensome and costly complication of deep venous thrombosis (DVT) that develops in 20-40% of patients within 1-2 years after symptomatic DVT. Affected patients have chronic leg pain and swelling and may develop ulcers. Venous valve disruption from the thrombus itself or thrombus-associated mediators of inflammation is considered to be a key initiating event for the development of venous hypertension that often underlies PTS. As existing treatments for PTS are extremely limited, strategies that focus on preventing the development of PTS in patients with DVT are more likely to be effective and cost-effective in reducing its burden. Elastic compression stockings (ECS) could be helpful in preventing PTS; however, data on their effectiveness are scarce and conflicting. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 5 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
Unknown | 89 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 13% |
Other | 12 | 13% |
Student > Bachelor | 11 | 12% |
Researcher | 10 | 11% |
Student > Ph. D. Student | 10 | 11% |
Other | 15 | 17% |
Unknown | 20 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 48 | 53% |
Nursing and Health Professions | 7 | 8% |
Engineering | 2 | 2% |
Psychology | 2 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 1% |
Other | 7 | 8% |
Unknown | 23 | 26% |