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Growth factor purification and delivery systems (PADS) for therapeutic angiogenesis

Overview of attention for article published in Vascular Cell, January 2015
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Title
Growth factor purification and delivery systems (PADS) for therapeutic angiogenesis
Published in
Vascular Cell, January 2015
DOI 10.1186/s13221-014-0026-3
Pubmed ID
Authors

Eric M George, Huiling Liu, Grant G Robinson, Fakhri Mahdi, Eddie Perkins, Gene L Bidwell

Abstract

Therapeutic angiogenesis with vascular endothelial growth factor (VEGF), delivered either via recombinant protein infusion or via gene therapy, has shown promise in preclinical models of various diseases including myocardial infarction, renovascular disease, preeclampsia, and neurodegenerative disorders. However, dosing, duration of expression, and tissue specificity are challenges to VEGF gene therapy, and recombinant VEGF delivery suffers from extremely rapid plasma clearance, necessitating continuous infusion and/or direct injection at the site of interest.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 22%
Student > Bachelor 5 16%
Researcher 5 16%
Student > Doctoral Student 3 9%
Student > Master 2 6%
Other 4 13%
Unknown 6 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 22%
Biochemistry, Genetics and Molecular Biology 4 13%
Medicine and Dentistry 4 13%
Nursing and Health Professions 3 9%
Engineering 2 6%
Other 4 13%
Unknown 8 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2015.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Vascular Cell
#47
of 72 outputs
Outputs of similar age
#221,168
of 359,707 outputs
Outputs of similar age from Vascular Cell
#1
of 3 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 72 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,707 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them