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The IL-10 polarized cytokine pattern in innate and adaptive immunity cells contribute to the development of FVIII inhibitors

Overview of attention for article published in BMC Hematology, January 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)

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1 blog
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1 X user

Citations

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10 Dimensions

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12 Mendeley
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Title
The IL-10 polarized cytokine pattern in innate and adaptive immunity cells contribute to the development of FVIII inhibitors
Published in
BMC Hematology, January 2015
DOI 10.1186/s12878-014-0019-8
Pubmed ID
Authors

Amanda CO Silveira, Marcio AP Santana, Isabella G Ribeiro, Daniel G Chaves, Olindo A Martins-Filho

Abstract

Hemophilia A (HA) is an X-linked inherited bleeding disorder, resulting from a qualitative or quantitative deficiency of clotting factor VIII (FVIII). Antibodies against FVIII, also called inhibitors, block the procoagulant activity of FVIII; thus, impairing hemostatic activity in patients with HA. The exact mechanism underlying the immunological events behind the development of inhibitors remains unknown. This study aimed to understand immune response to FVIII in patients with HA who were either positive [HAα-FVIII(+)] or negative [HAα-FVIII(-)] for inhibitors.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 33%
Student > Master 3 25%
Lecturer 1 8%
Student > Ph. D. Student 1 8%
Student > Doctoral Student 1 8%
Other 2 17%
Readers by discipline Count As %
Medicine and Dentistry 5 42%
Immunology and Microbiology 4 33%
Biochemistry, Genetics and Molecular Biology 1 8%
Veterinary Science and Veterinary Medicine 1 8%
Agricultural and Biological Sciences 1 8%
Other 0 0%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2017.
All research outputs
#3,978,736
of 22,786,691 outputs
Outputs from BMC Hematology
#10
of 81 outputs
Outputs of similar age
#57,266
of 352,396 outputs
Outputs of similar age from BMC Hematology
#1
of 3 outputs
Altmetric has tracked 22,786,691 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 81 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,396 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them