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Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair

Overview of attention for article published in Inflammation and Regeneration, March 2018
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2 X users

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33 Dimensions

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81 Mendeley
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Title
Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair
Published in
Inflammation and Regeneration, March 2018
DOI 10.1186/s41232-018-0061-1
Pubmed ID
Authors

Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka

Abstract

Articular cartilage has poor capacity for repair. Once damaged, they degenerate, causing functional impairment of joints. Allogeneic cartilage transplantation has been performed for functional recovery of articular cartilage. However, there is only a limited amount of articular cartilage available for transplantation. Mesenchymal stem cells (MSCs) could be potentially suitable for local implantation. MSCs can differentiate into chondrocytes. Several studies have demonstrated the therapeutic potential of MSCs in the repair of articular cartilage in animal models of articular cartilage damage and in patients with damaged articular cartilage. To boost post-implantation MSC differentiation into chondrocytes, the alternative delivery methods by scaffolds, using hyaluronic acid (HA) or poly-lactic-co-glycolic-acid (PLGA), have developed. In this review, we report recent data on the repair of articular cartilage and discuss future developments.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 81 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 20%
Student > Ph. D. Student 11 14%
Student > Master 9 11%
Student > Doctoral Student 8 10%
Researcher 8 10%
Other 8 10%
Unknown 21 26%
Readers by discipline Count As %
Engineering 15 19%
Biochemistry, Genetics and Molecular Biology 12 15%
Medicine and Dentistry 10 12%
Materials Science 7 9%
Agricultural and Biological Sciences 4 5%
Other 8 10%
Unknown 25 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2018.
All research outputs
#16,584,977
of 25,382,440 outputs
Outputs from Inflammation and Regeneration
#145
of 258 outputs
Outputs of similar age
#213,167
of 350,479 outputs
Outputs of similar age from Inflammation and Regeneration
#3
of 6 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 258 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 350,479 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.